Electrospinning is a simple and adaptable method for generating nanofibers. Due to the instability of the electrified polymer jet, polymer nanofibers are usually collected in random, tangled orientations. Alignment of nanofibers would have practical applications for use as cardiac tissue which have cells that grow in an aligned manner, as well as for neural tissue engineering as guidance channe...

Stem cell transplantations for spinal cord injury (SCI) have been studied extensively for the past decade in order to replace the damaged tissue with human pluripotent stem cell (hPSC)-derived neural cells. Transplanted cells may, however, benefit from supporting and guiding structures or scaffolds in order to remain viable and integrate into the host tissue. Biomaterials can be used as support...

It has been widely reported that chemical, structural or mechanical signals of biomaterials can impact cell behaviors and tissue regeneration, but few studies have investigated the effects of biomaterial signals on cell–cell interactions although communications between cells are critical for tissue regeneration. Our recent studies have shown that chemical signals of bioglass (BG) can stimulate ...

While most of the studies on molecular machines have been performed in solution, interfacing these supramolecular systems with solid-state nanostructures and materials is very important in view of their utilization in sensing components working by chemical and photonic actuation. Host polymeric materials, and particularly polymer nanofibers, enable the manipulation of the functional molecules c...

Abstract The spinning solution of PVA(polyvinyl alcohol) was chosen as the spiral research object. With enough needle length, macromolecules were straightened and aligned under laminar flow theory. controlled twisting macromolecules. motion trajectory titanium dioxide(nanoparticles) in nanofibers photographed by TEM(transmission electron microscope) action centripetal force, which directly veri...

In this study, we investigated the incorporation of poly(vinyl alcohol) (PVA) nanofibers within poly(methyl methacrylate) (PMMA) microchannels in order to allow for sample preparation and concentration within microfluidic detection systems. Nanofibers were electrospun onto gold microelectrodes and integrated into polymer microfluidic systems using ultraviolet (UV)-assisted thermal bonding. We d...