The paper presents an Adaptive Lattice Model (ALM) based on spatial constraints or resolution such as minimum object size and minimum spatial interval. An ALM represents GIS data by latticing adaptively the spatial space at a certain abstraction level or spatial resolution and omitting all details smaller or finer than the resolution. One implementation of ALM is called CELL, which considers ea...

To disseminate messages from a single source to a large number of targeted receivers, a natural approach is the tree-based application layer multicast (ALM). However, in time-constrained flash dissemination scenarios, e.g. earthquake early warning, where time is of the essence, the tree-based ALM has a single point of failure; its reliable extensions using ack-based failure recovery protocols c...

CpG oligodeoxynucleotides (ODN) have potent effects on innate and adaptive cellular immune responses. In this report, the ability of CpG ODN to confer long-term immunity and protection when used as a vaccine adjuvant with a clinical grade of leishmanial antigen, autoclaved Leishmania major (ALM), or a recombinant leishmanial protein was studied. In two different mouse models of L. major infecti...

BACKGROUND In cutaneous malignant melanoma (MM) with clinically uninvolved regional lymph nodes, sentinel lymph node (SLN) status is the most powerful indicator of both overall survival (OS) and disease-free survival (DFS). However, no studies on the long-term survival and clinical follow-up of Korean patients with acral lentiginous MM (ALM) undergoing SLN biopsy (SLNB) have been published. O...

Multicast communication model can be efficiently exploited by grid systems to improve the performance of many basic operations, like file transmission, replica management or resource discovery. However, IP multicast presents important limitations to be adopted in grid environments, since it is not fully supported in the Internet and is incompatible with TCP-based applications. In the last few y...

BACKGROUND Because body weight-bearing produces a shift in the horny layer, acral melanocytic nevus on the body weight-bearing area of the sole showed a regular fibrillar pattern (FP) due to slanting of the melanin columns in the horny layer. On the other hand, acral lentiginous melanoma (ALM) on the body weight-bearing area of the sole tended to show irregular fibrillar pattern showing rather ...

Activating mutations of the FLT3 gene occur because of an internal tandem duplication of the juxta-membrane domain (FLT3/ITD) or point mutation of the activation loop domain (FLT3/ALM). The presence of FLT3 mutations as well as the allelic ratio of FLT3/ITD (ITD-AR, mutant– wild type ratio) may have prognostic significance. FLT3 mutation status of 630 children with de novo acute myeloid leukemi...

Traditional approaches to simulate airflow movements in buildings are computationally expensive and do not achieve realtime prediction of results. This paper discusses an Adaptive Localization Method (ALM) that significantly minimizes the simulation domain to achieve close to real-time predictions. As the user interacts with the space by modifying boundary conditions (opening a window, etc.), w...

—Active Learning Method (ALM) is one of the powerful tools in soft computing that is inspired by human brain capabilities in processing complicated information. ALM, which is in essence an adaptive fuzzy learning method, models a Multi-Input Single-Output (MISO) system with several Single-Input Single-Output (SISO) subsystems. Ink Drop Spread (IDS) operator, which is the main processing engine ...

Skeletal muscle is a major component of the human body. Age-related loss of muscle mass and function contributes to some public health problems such as sarcopenia and osteoporosis. Skeletal muscle, mainly composed of appendicular lean mass (ALM), is a heritable trait. Copy number variation (CNV) is a common type of human genome variant which may play an important role in the etiology of many hu...