Let A be a factor von Neumann algebra and ? preserve n-tuple new product derivations on A, that is, for every A1,A2,... ,An ?(A1 A2 ?...? An) = ?(A1) An + A1 ?(A2) ?... ... ?(An) where Ai ?Aj A*iAj ?A*jAi i,j N, then is additive *-derivation, the condition ?(?I/2) self-adjoint operator {1,i}.

The IFN-alpha cytokines belong to a multigene family. However, the in vivo biological functions of each of the IFN-alpha subtypes is unknown. Recently, we developed an experimental model in which the tibialis anterior muscles of mice were transfected in situ with naked DNA plasmids encoding an IFN transgene. Here we use this model to investigate the in vivo effect of the expression of three mur...

This work aimed at investigating the lipid profile of zoonotic visceral leishmaniasis (VL) patients' sera and the effect of lipoproteins on the in vitro production of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6, IL-10 and IL-12 by Leishmania infantum-infected and uninfected macrophages. Lipids were quantified in 26 VL patients' sera and 26 healthy controls from a VL endemic are...

Studies of the incorporation of 14C amino acids into human lens proteins demonstrate that an alpha-crystallin fraction takes up more than six times as much radioactivity as any other lens protein. Based on analyses with a calibrated Bio-Gel A-1.5 m column, a molecular weight of 4.9 x 10(5) +/- 5 per cent was obtained for this protein while sedimentation equilibrium analyses indicated a weight a...

Let a1,a2,…,ak be positive integers with gcd(a1,a2,…,ak)=1. Frobenius number is the largest integer that NOT representable in terms of a1,a2,…,ak. When k?3, there no explicit formula general, but some formulae may exist for special sequences a1,a2,…,ak, including, those forming arithmetic progressions and their modifications. In this paper, we give power weighted sum nonrepresentable integers. ...

My research career started with snakes. For a year, from 1965 to 1966, Claes Hellerstr€ om and I worked together in herpetology (the branch of zoology that deals with amphibians, including frogs, toads, and reptiles). We joined forces with an SAS pilot, Captain Florin, who, between the flights to Los Angeles, was chairman of the Uppsala Herpetological Society. In his spare time, he collected ra...

Perisynaptic Schwann cells (PSCs) play critical roles in regulating and stabilizing nerve terminals at the mammalian neuromuscular junction (NMJ). However, although these functions are likely regulated by the synaptic properties, the interactions of PSCs with the synaptic elements are not known. Therefore, our goal was to study the interactions between mammalian PSCs in situ and the presynaptic...

One of the most common cancers worldwide is oral squamous cell carcinoma (OSCC), which is associated with a significant death rate and has been linked to several risk factors. Notably, failure to detect these neoplasms at an early stage represents a fundamental barrier to improving the survival and quality of life of OSCC patients. In the present study, serum samples from OSCC patients (n = 25)...

The RNA-recognition motif (RRM) is a common and evolutionarily conserved RNA-binding module. Crystallographic and solution structural studies have shown that RRMs adopt a compact alpha/beta structure, in which four antiparallel beta-strands form the major RNA-binding surface. Conserved aromatic residues in the RRM are located on the surface of the beta-sheet and are important for RNA binding. T...