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Patients affected by cerebral gliomas, despite classical strategies adopted, show a very poor prognosis. Current treatment consists of regimens that include surgical debulking, radiation therapy, and systemic chemotherapy. However, the median survival after surgery and radiation therapy alone is 9 months, and systemic chemotherapy is minimally effective. Advances in molecular biology have bette...
A new form of the Kerr-Newman solution is presented. The involves a time coordinate which represents local proper for charged massive particle released from rest at spatial infinity. chosen coordinates ensure that well-behaved horizons and enable an intuitive description many physical phenomena. If charge $e = 0$, reduce to Doran Kerr with replacement $M \to M - Q^2/(2r)$, where $M$ $Q$ are mas...
The G2 DNA damage and slowing of S-phase checkpoints over mitosis function through tyrosine phosphorylation of NIMX(cdc2) in Aspergillus nidulans. We demonstrate that breaking these checkpoints leads to a defective premature mitosis followed by dramatic rereplication of genomic DNA. Two additional checkpoint functions, uvsB and uvsD, also cause the rereplication phenotype after their mutation a...
Communications for this section will he published as space and priorities permit. The comments should not exceed 350 words in length, with a maximum of five references; one figure or table can be printed. Exceptions may occur under particular circumstances. Contributions may include comments on articles published in this periodical, or they may be reports of unique educational character. Specif...
I COMPARE TWO POSSIBLE EXTREME HYPOTHESES REGARDING SUBMISSION OF PAPERS TO JOURNALS: the Q hypothesis, whereby the decision to submit is based on quality of research; and the P hypothesis, whereby it is based on probability of acceptance. I give five reasons as to why the P hypothesis is more plausible and suggest that problems of missing data may previously have caused researchers to misinter...
one of the most importanat traits of fluorescent pseudomonads, a phenomenon also related to their biocontrol, is the ability to develop phase variation during their rhizosphere colonization. for an investigation of this phenomenon, at first 24 bacterial strains of pseudomonas fluorescens that were able to cause an inhibiting zone within the range of 3-14.67 mm. against gaeumannomyces graminis v...
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