Accurate structure factors have been measured for the two known conformational polymorphs (A and B) of famotidine up to a maximum resolution of sin(theta)/lambda = 1.2 A(-1) at 100 K using a conventional X-ray source and a CCD-based diffractometer. The experimental electron-density distribution was modelled using a multipole model and the interatomic interactions were analysed following the ato...

The extent of aluminium internalization during the recovery from aluminium stress in living roots of Arabidopsis thaliana was studied by non-invasive in vivo microscopy in real time. Aluminium exposure caused rapid depolarization of the plasma membrane. The extent of depolarization depends on the developmental state of the root cells; it was much more extensive in cells of the distal than in th...

The study demonstrates two approaches in formulation of solid oral lipid-based diazepam preparations (BCS class II drug). The aim of the study was to formulate tablets and hard capsules, using emulsifier and adsorbent. Lipidbased preparations improve drug solubility and permeability, i. e. bioavailability. Solid silicate carriers are able to adsorb liquid lipid formulations, resulting in freely...

Aluminium is the most abundant metal and constitutes 8% of the earth’s crust. It is a normal constituent of vegetable and animal tissues and is present in raw untreated water. In domestic tap-water supplies, aluminium may be present in high concentrations either from its presence in raw water or, more commonly, as a result of its use during the water-purification process. Aluminium in the metal...

A computationally driven experimental search for polymorphs of 3-hydroxybenzoic acid confirmed the third form and small energy differences between polymorphs.

Objective—To investigate possible neurotoxic eVects in groups of aluminium pot room and foundry workers, aluminium welders, and a small group of workers exposed to aluminium in the production of flake powder. Methods—Exposure to aluminium was evaluated with aluminium concentrations in blood and urine as well as a questionnaire. The groups exposed to aluminium were compared with a group of mild ...

OBJECTIVE To investigate possible neurotoxic effects in groups of aluminium pot room and foundry workers, aluminium welders, and a small group of workers exposed to aluminium in the production of flake powder. METHODS Exposure to aluminium was evaluated with aluminium concentrations in blood and urine as well as a questionnaire. The groups exposed to aluminium were compared with a group of mi...

The aim of this paper is to focus on the effect of cryogenic treatment on the microstructure, mechanical and wear properties of Al 6061 and Al 8011.  The first objective was to understand the degree to which hardness of these aluminium grades have been enhanced by giving  cryogenic on the specimens. The second objective is to check the wear resistance property of these two aluminium specimens i...