In patients experiencing an acute episode of hypersensitivity pneumonitis (HP), the alveoli and interstitium show a marked inflammation. The effects of this infiltration with effector cells on gas exchange and the cardiopulmonary system are not well characterized, and there are no data regarding cardiopulmonary exercise testing during hypersensitivity pneumonitis. The aim of this study was to g...

In the present investigation, methanolic extract of Mimusops elengi  leaves were evaluated for wound healing activity. Entire wound healing process is complex series of events that begins at the moment of injury and can continue for months to years. Methanolic extract of Mimusops elengi leaves were examined for wound healing activity in the form of ointment by the excision, the incision and ...

BACKGROUND The impact of humidification devices on ventilatory and arterial blood gases parameters during noninvasive ventilation (NIV) remains controversial. The aim of the study was to compare the short-term impact of heat and moisture exchangers (HMEs) and heated humidifiers (HHs) during NIV for either hypercapnic or hypoxemic acute respiratory failure. METHODS Consecutive subjects receiv...

This study was performed to elucidate the mechanism of improved oxygenation after surfactant replacement therapy in respiratory distress syndrome (RDS) of the newborn infants. In 26 newborns with RDS, end tidal-CO2 tension (PetCO2), arterial blood gas analysis and pulmonary function tests were measured at baseline, 30 min, 2 hr and 6 hr after surfactant administration. The changes in dead space...

The device described in this study uses functionally variable dead space to keep effective alveolar ventilation constant. It is capable of maintaining end-tidal PCO(2) and PO(2) within +/-1 Torr of the set value in the face of increases in breathing above the baseline level. The set level of end-tidal PCO(2) or PO(2) can be independently varied by altering the concentration in fresh gas flow. T...

results sixty patients were involved in this study. in asv mode, values including peak airway pressure (p-peak), end-tidal carbon dioxide (etco2), tidal volume and respiratory dead space were significantly lower than simv mode. although the mean value for dynamic compliance had no significant difference in the two types of ventilation, it was better in asv mode. methods in a crossover study, pa...

The official statements of the European Respiratory Society (ERS) [1] and American Thoracic Society (ATS) [2] consistently recommended some corrections before adopting the measured values of alveolar helium fraction (FA,He) in the "alveolar sample" for the calculation of alveolar volume (VA). I refer to the measurement of the carbon monoxide transfer factor by the single-breath method. As the e...