3,5-dinitro-benzoyl chloride was refluxed with different amino acids to form the amino acid derivatives that were reduced with zinc/formic acid, to form the products and the reduced products so formed were cyclized to give the title compounds with benzil in the presence of sodium ethoxide/ethanol. All the intermediates and title compounds were characterized by physical, chemical, analytical and...

Diazo compounds, boranes, and acyl imines undergo a three-component Mannich condensation reaction under catalyst-free conditions to give the anti β-amino carbonyl compounds in high diastereoselectivity. The reaction tolerates a variety of functional groups, and an asymmetric variant was achieved using the (-)-phenylmenthol as chiral auxiliary in good yield and selectivity. These β-amino carbony...

Today, the majority of drugs used in treatment diseases are obtained by synthesis. A large proportion compounds have heterocyclic structure. Therefore, synthesis new has always attracted and continues to attract scientist. It is known that bearing triazole skeleton an important place. The reactions 4-amino-triazole compounds, especially with aromatic aldehydes, been for a long time this reactio...

ABSTRACT. Quorum sensing (QS), used by many pathogenic bacteria to express virulence factors, is seen as a new and effective strategy combat resistant bacteria. In this study, theoretical investigations were made on the structural data of molecules support inhibition effects 2-amino 4-chloro benzoic acid 4-amino 2-chloro molecules. Theoretical calculations performed using density functional the...