Background. Viral hepatitis is one of the most common and dangerous diseases in world third infectious disease. The development new, more effective safer hepatoprotective drugs an urgent task biomedicine. A wide range proven biological properties cryoextract human placenta, particular presence antioxidant, immunomodulating anti-inflammatory effects, suggests that it has a effect. model D-galact...

Investigations showed the haemoglobin to be 12 gmldl, leucocyte count of 22,000 with 60% polymorphs, 40% lymphocytes, and platelets 105,000/mm 3. Blood urea was 2.6 mmolll, glucose 0.8 mmolll, serum sodium 110 mmolll, potassium 5.3 mmolll. The prothrombin time was 10% of normal and serum bilirubin 104 umolll (conjugated 30 umol/l). The aspartete and alanine aminotransferases were 550 lUll and 5...

Although several powerful methods exist for the redesign of enzyme structure and function these are typically limited to the 20 most abundant proteinogenic amino acids. The use of chemical modification overcomes this limitation to allow virtually unlimited alteration of amino acid sidechain structures. If heterogeneous mixtures of enzyme products are to be avoided, however, the required chemist...

The effect of aqueous ethanol (1:1) extract of the calyx of Hibiscus sabdariffa on carbon tetrachloride (CCl4) induced liver damage was investigated. Oral administration of the extract following a single CCl4 dose promoted the healing of oxidative liver damage as determined by serum aminotransferases, ALT, AST, levels and liver thiobarbituric acid reactive substances levels. It appeared from th...

The activities of phenylalanine p-hydroxylase, tyrosine: alpha-ketoglutarate and phenylalanine: pyruvate aminotransferases, and aromatic alpha-ketoacid reductase have been measured in liver biopsies obtained from children with a series of disorders other than phenylketonuria and from human foetuses aged 8.5 to 24 weeks. The importance of such a study in relation to the management of infants wit...

liver functional tests due to inflammatory process which induced by cholecystitis might changed and some clinicians suggested that these changes might help us to stone prediction in common bile ducts and decrease hazards of performing ercp and other invasive procedures. present study was performed for assessment of role of liver functional test in diagnosis of common bile duct stone in patients...

A 56 year old man presented with an atypical chest infection. Remote inferoposterior myocardial infarction was noted on electrocardiography and transthoracic echocardiography. Hepatic failure developed with sudden gross elevation of liver aminotransferases and coagulopathy. No primary hepatic cause could be identified. Subsequent right heart failure led to transoesophageal echocardiography that...