نتایج جستجو برای: amol
تعداد نتایج: 672 فیلتر نتایج به سال:
results the prevalence of hbsag, hbsab and hbcab were estimated as 0.9%, 30.7% and 10.5%, respectively. the mean age of all participants was 43.9 (95% ci: 43.4, 44.3) in females and 55.6 in (n = 3472) males. in our study, there was a significant association between family history of hepatitis, rural residency and presence of hbsag. there was also a positive correlation between hbcab and family ...
Early detection of cancer biomarkers applied in real-time disease diagnosis and therapies can increase the survival rate patients. Circulating tumor DNA (ctDNA) as a typical biomarker plays great role process monitoring, especially early diagnosis. Unfortunately, most ctDNA systems have not been widely used due to their low sensitivity, poor specificity, high cost. Herein, we developed an alter...
The emerging field of plasmonic metamaterials has introduced new degree of freedom to manipulate optical field from nano to macroscopic scale, offering an attractive platform for sensing applications. So far, metamaterial sensor concepts, however, have focused on hot-spot engineering to improve the near-field enhancement, rather than fully exploiting tailored material properties. Here, we prese...
A novel microarray system that utilizes a porous aluminum-oxide substrate and flow-through incubation has been developed for rapid molecular biological testing. To assess its utility in gene expression analysis, we determined hybridization kinetics, variability, sensitivity and dynamic range of the system using amplified RNA. To show the feasibility with complex biological RNA, we subjected Jur...
This paper studies patient volume and the severity of case mix as they relate to physicians’ human capital accumulation and pace of technology adoption by exploring a quality signaling mechanism through which physicians build peer reputation. We show that volume building leads physicians to actively manage case mix and find that successful surgeries (particularly for difficult cases) raise futu...
One challenge in point-of-care (POC) diagnostics is the lack of room-temperature methods for RNA detection based on enzymatic amplification and visualization steps. Here we perform reverse transcription lesion-induced DNA (RT-LIDA), an isothermal method that only requires T4 ligase. RT-LIDA involves RNA-templated ligation primers to form complementary (cDNA) followed by toehold-mediated strand ...
DNA microarrays are invaluable tools for biosensing applications such as diagnostic detection of DNA and analysis of gene expression. Surface plasmon resonance imaging can detect unlabeled oligonucleotide targets adsorbed to the array elements. The variety of biosensing applications can be expanded by enzymatic manipulation of DNA microarray elements, and the sensitivity of detection can be enh...
Nicotinic receptor-mediated secretion of catecholamines from individual cultured bovine adrenal medullary chromaffin cells was measured and characterized with a voltametric microelectrode placed adjacent to the cells. Nicotine-induced secretion is associated with a large increase in chemical spikes that is temporally resolved into the apparent secretion of discrete packets of attomole quantitie...
In recent years, groundwater quality has become a global concern due to its effect on human life and natural ecosystems. To assess the groundwater quality in the Amol-Babol Plain, a total of 308 water samples were collected during wet and dry seasons in 2009. The samples were analysed for their physico-chemical and biological constituents. Multivariate statistical analysis and geostatistical te...
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