Aims To ascertain the effect of SARS-CoV-2 on utilisation antibacterial agents and analgesics in primary dental care. Methods Antibacterial (eg paracetamol, aspirin) prescribed England by general practitioners for periods April-July 2019 2020 were analysed. Results during COVID-19 restrictions (799,282) higher than a similar time period (654,332) 22%. Amoxicillin was used most (2020 = 65.0%; 66...

A 25-year-old non-smoking warehouse worker presented to the acute medical take with a five-day history of worsening symptoms including anorexia, lethargy, myalgia, swinging fevers and night sweats. He had been seen by his general practitioner at the start of this illness and commenced on oseltamivir to treat presumed H1N1 influenza; subsequent hospital referral was prompted by worsening oral in...

BACKGROUND Restriction of antibiotic consumption to below predefined total use thresholds might remove the selection pressure that maintains antimicrobial resistance within populations. We assessed the effect of national antibiotic stewardship and infection prevention and control programmes on prevalence density of meticillin-resistant Staphylococcus aureus (MRSA) infections across a region of ...

OBJECTIVES To systematically review studies investigating the prevalence of antibiotic resistance in urinary tract infections caused by Escherichia coli in children and, when appropriate, to meta-analyse the relation between previous antibiotics prescribed in primary care and resistance. DESIGN AND DATA ANALYSIS Systematic review and meta-analysis. Pooled percentage prevalence of resistance t...

The effects of co-amoxiclav (AMC) and amoxicillin (AMX) therapy on the nasopharyngeal flora of children with acute otitis media (AOM) were compared. Nasopharyngeal culture for aerobic and anaerobic bacteria were obtained before therapy and 2-4 days after completion of antimicrobial therapy in 25 patients treated with either antibiotic. After therapy, 16 (64%) of the 25 patients treated with AMX...

We describe the trend of antibiotic prescribing in out-of-hours (OOH) general practices (GP) before and during England’s first wave COVID-19 pandemic. analysed practice-level records between January 2016 to June 2020 report trends for total volume, broad-spectrum antibiotics key agents included national Quality Premium. performed a time-series analysis detect measurable changes volume associate...

OBJECTIVES A Trust strategy to reduce ciprofloxacin use was implemented at a University hospital. This study aimed to investigate whether the susceptibility of Gram-negative organisms (GNO) to alternative antimicrobials (co-amoxiclav, doxycycline, aztreonam, piperacillin/tazobactam, meropenem and gentamicin) changed, and whether there was any relationship between GNO susceptibility to these ant...