Abstract. Porous poly(N-isopropylacrylamide) (PNIPAAm) hydrogels with pore diameters in the nanometer and micrometer range were synthesized using two variations of surfactant-based template method. We showed that smaller lead to faster swelling deswelling. A graphic representation a model describing kinetics explains assumption release uptake water is for larger specific surface area, diameters...

In a previous communication, we showed that beta-adrenergic stimulation of cardiac muscles was associated with an increase in the rate of cycling of crossbridges as measured by perturbation analysis in the frequency domain. In this analysis, the frequency at which dynamic stiffness is a minimum (fmin) is taken as a measure of the rate of crossbridge cycling. In this paper, we test the hypothesi...

Adenylate kinase and downstream AMP signaling is an integrated metabolic monitoring system which reads the cellular energy state in order to tune and report signals to metabolic sensors. A network of adenylate kinase isoforms (AK1-AK7) are distributed throughout intracellular compartments, interstitial space and body fluids to regulate energetic and metabolic signaling circuits, securing effici...

In a previous communication, we showed that 3-adrenergic stimulation of cardiac muscle was associated with an increase in the rate of cycling of crossbridges as measured by perturbation analysis in the frequency domain. In this analysis, the frequency at which dynamic stiffness is a minimum (f.in) is taken as a measure of the rate of crossbridge cycling. In this paper, we test the hypothesis th...

In a previous communication, we showed that 3-adrenergic stimulation of cardiac muscle was associated with an increase in the rate of cycling of crossbridges as measured by perturbation analysis in the frequency domain. In this analysis, the frequency at which dynamic stiffness is a minimum (f.in) is taken as a measure of the rate of crossbridge cycling. In this paper, we test the hypothesis th...

Researchers have recently questioned the role hydroxylated prolines play in stabilizing the collagen triple helix. To address these issues, we have developed new molecular mechanics parameters for the simulation of peptides containing 4(R)-fluoroproline (Flp), 4(R)-hydroxyproline (Hyp), and 4(R)-aminoproline (Amp). Simulations of peptides based on these parameters can be used to determine the c...

A portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion that results in hepatic 5-aminoimidazole-4-carboxamide-1-beta-D-ribosyl-5-monophosphate (ZMP) concentrations of approximately 4 micromol/g liver increases hepatic glycogenolysis and glucose output. ZMP is an AMP analog that mimics the regulatory actions of this nucleotide. The aim of this study was to measure hepati...

Mobile agents are autonomous software entities driven by a set of goals and tasks. Reactivity, social ability, autonomy, the ability to move to different network locations, and the weak agent notion of proactiveness, allow for autonomous processing of distributed information according to their environment (context awareness). Although agent mobility has been devised for homogeneous environments...

Abstract. The heterogeneous reaction of N2O5 on Cl-containing aerosols (heterogeneous + Cl chemistry) plays a key role in chlorine activation, NOx recycling, and consequently O3 PM2.5 formation. In this study, we use the GEOS-Chem model with additional anthropogenic biomass burning emissions combined updated parameterizations for chemistry (i.e., uptake coefficient (γN2O5) ClNO2 yield (φClNO2))...