Background & Objective: The her2 amplification plays an important role in breast cancer management. Therefore, there is a need for using supplementary molecular methods in IHC equivocal cases. Present study has been conducted to determine the effects of clinicopathological variables on her2 gene amplification by chromogenic in situ hybridization (CISH) in IHC ...

Background: Amplification of HER2 is seen in 20-30% of breast cancer cases. Measurement of HER2 gene amplification appears to be of vital importance in planning the treatment schedule for patients with breast carcinoma. The aim of our study was to evaluate HER2 amplification status in malignant and benign breast tumors by differential PCR (dPCR). Materials and Methods: The genomic DNA was ex...

charcot-marie-tooth disease (cmt) is the most common inherited neurological disorder, affecting both motor and sensory peripheral nerves. neurophysiological patterns divide cmt into three main groups: demyelinating cmt1 (upper limb motor nerve conduction velocity (mncv) <38 m/s), axonal cmt2 (mncv >38 m/s) and intermediate cmt (mncv 25-45 m/s). cmt has been also categorized based on the mode of...

with the prolonged use of domestic centrifugal pump, due to erosion, corrosion and an unbalance the sever vibration of the pump are resulted. an erratic sound coming out of pump makes the user uncomfortable. here, tuned vibration absorber (tva) is used as a vibration controlling device. it is designed to reduce the rms velocity below 20% of the circumferential speed, at which the impeller is ba...

conclusions nucleic acid amplification tests (naats) are very appropriate in detection of infected individuals. detection techniques such as naats are independent of bacterial viability, and have a potential to limit false negative samples, therefore, in our country, the application of different laboratory diagnosis methods including naats with culture as gold standard for determination antimic...

in this paper, an advanced formulation of the spectral finite element method (sfem) is presented and applied in order to carry out site response analysis of 2d topographic structures subjected to vertically propagating incident in-plane waves in time-domain. the accuracy, efficiency and applicability of the formulation are demonstrated by solving some wave scattering examples. a numerical param...

Intelligent reflecting surfaces (IRSs), active and/or passive, can be densely deployed in complex environments to significantly enhance wireless network coverage for both information transfer (WIT) and power (WPT). In this letter, we study the downlink WIT/WPT from a multi-antenna base station single-antenna user over multi-active/passive IRS (AIRS/PIRS)-enabled link. particular, derive locatio...

Abstract Each Galileo satellite provides coherent navigation signals in four distinct frequency bands. International GNSS Service (IGS) analysis centers (ACs) typically determine products based on the E1/E5a dual-frequency measurements due to software limitation and limited tracking capability of other early time. The goal this contribution is evaluate quality determined by using different (E1/...