A total of 63 women who had an operation for a fracture of the hip was randomly allocated to one year of treatment either with anabolic steroids, vitamin D and calcium (anabolic group) or with calcium only (control group). The thigh muscle volume was measured by quantitative CT. The bone mineral density of the hip, femur and tibia was assessed by quantitative CT and dual-energy x-ray absorptiom...

Anabolic-androgenic steroids (AAS) are synthetic derivatives of testosterone. According to surveys and media reports, the legal and illegal use of these drugs is gaining popularity. Testosterone restores sex drive and boosts muscle mass, making it central to 2 of society's rising preoccupations: perfecting the male body and sustaining the male libido. The anabolic effects of AAS have been quest...

Undoubtedly, problems exist at present because of the long time needed between collection of urine samples and the completion of the first analysis and re-check analysis for the B sample when large numbers of samples are being processed for anabolic steroid control. Current research will shorten this time and also will increase the duration of the period between discontinuing the use of anaboli...

The synthetic anabolic steroids have structural features which distinguish them from the natural steroid hormones. It should therefore be possible to detect the taking of these substances by testing for their presence in either blood or urine. At present suitable techniques include gas chromatography, mass spectrometry and radioimmunoassay. For practical and psychological reasons urine tests ar...

The Commonwealth of Pennsylvania regulates the use of anabolic and androgenic steroids by monitoring plasma samples obtained from equine athletes post competition. Plasma samples were chosen over urine because the pharmacological action of any drug is generally based on plasma concentration of the parent or active metabolite of the compound and not its concentration in urine. Furthermore, the c...

Detecting the use of androgenic anabolic steroids, potentially endogenous in humans, and which are prohibited substances in sport doping control programmes, still represents a major challenge to the analysts. These steroids include testosterone, its precursors androstenedione and dehydroepiandrosterone, and the 19-norsteroids equivalents, some of which are commercially available for oral self-a...