1Academy of Animal Science and Veterinary Medicine, Qinghai University, Xining, People’s Republic of China, 2College of Life Science and Technology, Southwest University for Nationalities, Chengdu, People’s Republic of China, 3College of Agricultural and Animal Husbandry, Qinghai University, Xining, People’s Republic of China, 4Department of Biosciences, Qinghai University, Xining, People’s Rep...

Carboxylesterase (CES) 1 and CES2 are two major hepatic hydrolases responsible for the metabolism of numerous endogenous and exogenous compounds. In this study, age- and sex-dependent expression and activity of CES1 and CES2 were investigated using both animal models and individual human liver s9 samples. The expression and activity of mouse CES1 (mCES1) and mCES2 in the liver were markedly low...

Using animal models of acinar and ductal pancreatic cancer, we investigated the effect of analogs of hypothalamic hormones on tumor growth. In Wistar/Lewis rats bearing the acinar pancreatic tumor DNCP-322, chronic administration of [L-5-Br-Trp8]somatostatin-14 significantly decreased tumor weights and volume. Somatostatin-28 and the cyclic hexapeptide analog of somatostatin cyclo(Pro-Phe-D-Trp...

Plant hormones have been studied for more than a century because they have been heavily implicated in the control of plant growth and development. For many years, they have been considered to fall into five classes: auxins, cytokinins, gibberellins, abscisic acid and ethylene. More recently, a variety of additional classes such as brassinosteroids have been added and it seems likely that more w...

As part of an investigation of regulatory mechanisms in fatty acid metabolism, a study was undertaken of the effects of the growth hormone of the pituitary gland. The well established ketogenic action of this hormone (l-6), its fat-mobilizing and respiratory quotient-lowering effects (7-12), its growth-promoting activity whereby the protein content of an animal is increased at the expense of bo...