Conventional histological analyses are the gold standard for study of aneurysms and vascular pathologies in pre-clinical research. Over past decade, vivo ex imaging using multiphoton microscopy have emerged as powerful tools detailed tissue that can assess morphology, extracellular matrix (ECM), cell density vascularisation. Multiphoton allows deeper penetration with minor phototoxicity. The pr...

A new trigonotarbid (Arachnida: Trigonotarbida: Trigonotarbidae) is described as Archaeomartus roessleri n. sp. from the Upper Carboniferous (Pennsylvanian; Namurian B, higher Marsdenian) of Hagen-Vorhalle, Germany. Originally assigned to Trigonotarbus johnsoni Pocock, 1911, our new fossil has a distinctly lobed carapace and thus resembles more closely the Early Devonian species Archaeomartus l...

OBJECTIVES To investigate the presence and the genetic environment of the multiresistance gene cfr in naturally occurring Gram-negative bacteria of pigs. METHODS A total of 391 bacterial isolates with florfenicol MICs of ≥16 mg/L, obtained from 557 nasal swabs of individual pigs, were screened by PCR for the known florfenicol resistance genes. The species assignment of the cfr-carrying isolat...

Pseudomonas aeruginosa is an opportunistic human pathogen that colonizes the lungs of cystic fibrosis (CF) patients. CF lungs often contain a diverse range of P. aeruginosa phenotypes, some of which are likely to contribute to the persistence of infection, yet the causes of diversity are unclear. While the ecological heterogeneity of the lung environment and therapeutic regimes are probable fac...

Plant cell growth regulation Piezo sensors in animal cells are localized the membrane and transduce mechanical signals. The of plant cells, unlike that is usually plastered up against a stiff wall does not have much mobility. Much cell’s volume accounted for by large central vacuole, which, tonoplast, so mechanically constrained. Radin et al . studied how where use sensors. homologs mechanosens...

Last Updated: August 2013 Importance Rat bite fever is a human illness that can be caused by two different bacteria, Streptobacillus moniliformis and Spirillum minus. Although this disease is readily cured with antibiotics, untreated infections are sometimes fatal. Both S. moniliformis and Sp. minus are acquired primarily from rodents, especially rats. At one time, rat bite fever was mainly a h...

Francisella tularensis is a CDC Category A biological agent and a potential bioterrorist threat. There is no licensed vaccine against tularemia in the United States. A long-standing issue with potential Francisella vaccines is strain phase variation to a gray form that lacks protective capability in animal models. Comparisons of the parental strain (LVS) and a gray variant (LVSG) have identifie...

In order to assess the effect of eruption rate on the surface morphology and degassing mechanisms of silicic lava flows, we studied surface characteristics and obtained water content and hydrogen isotopic values of samples from flows at the Mount St. Helens and Santiaguito lava domes. We compared the surface textures and inferred degassing processes to short-term extrusion rates and found that ...