Objective: The purpose of the current study was to investigate the in vivo (analgesic, antidiarrheal, neurological, and cytotoxic) and in vitro (antioxidant, antimicrobial, thrombolytic and anthelmintic) activity of different fractions of methanolic extract of Momordica charantia. Materials and Methods: The antioxidant property ...

It was evaluated the anthelmintic activity of Agave sisalana (sisal) juice against gastrointestinal nematodes and its potential toxic effects in goats. In vitro tests showed more than 95% reduction in larval counts of the genus Haemonchus spp. at concentrations between 86.5 and 146.3 mg.mL(-1). In vivo the percent reduction of larvae of the fourth (L4) and fifth (L5) stages of Haemonchus, Oesop...

On a pharmacological screening, substantial antibacterial, antifungal and anthelmintic activities were observed for the hexane and ethyl acetate extracts of the root barks of Uvaria narum Wall. and Uvaria hookeri King. Chromatographic fractionation of these extracts led to the isolation of the triterpenes glutinol, glutinone, taraxerol, beta-sitosterol and Annonaceous acetogenins uvariamicins-I...

Chemotherapy remains the foremost available tool for the control of nematode parasites. However, the substantial use of anthelmintics, combined with a scarcity of new anthelmintic classes, has led to a gradual increase in the resistance of nematode parasites to these compounds. Multi-Drug Resistance (MDR) in economically important livestock nematodes, such as Haemonchus contortus enables the pa...

Two morphologically marked strains of Haemonchus contortus, CAVRS (smooth-macrocyclic lactone resistant) and McMaster (linguiform-macrocyclic lactone susceptible), were used to investigate the selection for anthelmintic resistance following exposure to ivermectin (IVM), a non-persistent anthelmintic. and a more persistent anthelmintic, oral moxidectin (MOX). Three types of selection were invest...

Tephrosia purpurea is a copiously branched herbaceous perennial plant distributed throughout the tropics which is used in the treatment of bronchitis, diuretic, pimples, tonic, laxative, cough, and tumour. The present study is an attempt to explore the anthelmintic activity of aqueous and methanolic extract of leaves of plant Tephrosia purpurea . The various concentrations of aqueous and methan...

In the world of therapeutics certain drugs or preparations have been used for so many years that the statements in the literature, especially in the textbooks and also in articles in professional journals, as to the action of these drugs have a tendency to reiterate impressionistic ideas or traditions. Printed statements are ordinarily copied and passed on with little or no attempt to substanti...

The objective of this study was to assess the efficacy commercial anthelmintics in horses naturally infected with gastrointestinal nematodes from southern Rio Grande do Sul state, Brazil. anthelmintic assessed by fecal egg count reduction test (FECRT) and coproculture. Fecal samples were collected 110 animals seven farms located region state Sul, south Criteria used suspect resistance included ...

Leche de higueron is the sap of the Ficus ZuurifoZia (1, 2)) a tree which is very closely related to the domestic fig tree.’ It has been widely used as a general anthelmintic by the natives of South America and Panama and its anthelmintic action confirmed by several medical investigators who have noticed that it was particularly effective against Trichuris trichiura. The most recent work on thi...