Cancer is still a problem and needs to be solved in all over the world. One of most commen cancers which experienced by women cervical cancer. Therefore, alternative therapies derived from natural ingredients such as sablo plant are needed that have potential developed an anti-cancer. This study evaluated antiproliferative activity extract fractions leaves cancer HeLa cells with Cell Counting K...

Background: Lenalidomide, a synthetic immunomodulatory drug, has a wide range of features including anti-angiogenic and anti-proliferative properties. To date, researchers have shown that lenalidomide is capable of ameliorating the immune system factors and antitumor responses. Most researchers have reported that lenalidomide enhances the immune response in certain cancer patients through sever...

This article refers to:A new Er(III)-based MOF showing anti-colon cancer activity by inhibiting IL-6-STAT3 signaling pathway and reducing TNF-α IL-1β production

flavonoids are wide range of phytochemical with various pharmacological effects including antioxidant, anti-inflammation, anti-platelet, anti-allergic, cytotoxicity, reduce risk for heart disease or cancer etc. these flavonoids inhibited various enzymes such as prostaglandin synthase, lypoxygenase, cyclooxygenase, and induced detoxifying enzyme systems such as glutathione s-transferase. flavono...

Topoisomerase is one of the most important targets anti-cancer drugs. In order to develop effective and low-toxic topoisomerase inhibitors, a series xanthone derivatives have been designed synthesized using principles skeleton transition. vitro cytotoxicity assays human breast cancer (MCF-7), gastric (MGC-803), cervical cancer(Hela) cell lines, compounds showed antitumor growth activity, also l...

objective(s):sea cucumber is one of the classes of echinoderms, which is considered as a health marine product and possess various biological characteristics with therapeutic application. the present investigation attempted to evaluate the potential of anti-cancer persian gulf sea cucumber species holothuria arenicola (h. arenicola) aqueous extract on mice colon carcinoma cells in vitro and in ...

background: bleomycin (blm) is an anti-cancer drug widely used in the treatment of cancer. blm causes several side effects related to dna and cellular damage. the aim of this study was investigated the effects of tea polyphenol epicatechin on anti-proliferative effects induced by bleomycin in human normal skin and human ovarian cancer cells.materials and methods: human ovarian cancer cell (skov...

background: anti-angiogenic therapy is a crucial step in cancer treatment. the discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. because little data correlated to the pro- and anti-angiogenic efficacies of ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...