Malaria is a major threat to public health and economic development in Africa. Current estimates indicate that at least one to three million children die of malaria each year in Africa alone. Efforts to eradicate malaria have failed and parasite resistance to the most commonly used and affordable anti-malarial drugs is developing rapidly. Insecticide resistance in the vector is also an evolving...

Malaria is one of the most common major health problems all over the world. Pharmacotherapy is the most common treatment strategy for the disease. But, the main obstacle behind this is emergence of resistance for many of these drugs. Hence, to overcome this problem, the major option available since ancient times is medicinal plants all over the world. Mankind is blessed with wide range of herba...

A 30-year-old Japanese woman with falciparum malaria was hospitalized because of fever and renal failure, and prolonged anemia was identified despite the eradication of malaria parasites through anti-malaria therapy. Bone marrow aspiration revealed the presence of macrophages with hemophagocytosis, and serum interleukin (IL)-18 and tumor necrosis factor (TNF)-alpha levels were high in the anemi...

Papaya (Carica papaya L.) is well known for the its exceptional nutritional and medicinal properties throughout world. From past, whole plant including leaves, seeds, ripe unripe fruits their juice used as a traditional medicine. The fruit has large oval shape, yellowish – green yellow flesh. Phytochemically it contains enzymes papain, chymopapin, which biologically actives value. They also con...

introduction malaria is the most important parasitic infection, which is now spread all over the globe. malaria infections with more than two species, especially plasmodium falciparum and p. vivax, are common, but infections with p. malariae and p. falciparum are rare. discussion mixed malaria infection is not uncommon, and it needs to be diagnosed and treated effectively in order to control th...

Traditional medicinal plants are a possible source of anti-malarial and anti-typhoid medications, there is growing interest in the usage development herbal therapies for these ailments. The study aims to investigate anti-malaria properties of Dryopteris dilataa leaves silico. plant were extracted ethanol analyzed using Fourier transform infrared spectrometer (FTIR) gas chromatography-mass ...

In this study, we show that 40.29% of travellers with a possible history of malaria exposure were positive for anti-Plasmodium spp. antibodies, while these individuals were negative by microscopy. The antibody test described here is useful to elucidate malaria exposure in microscopy-negative travellers from endemic countries.

The aim of the study is to present the efforts of the Greek physicians to introduce a malaria control and eradication program in Greece. It is based on the proceedings of the Greek Anti-Malaria League and on medicohistorical studies. Due to political, economic and military reasons the Greek State seemed weak to develop a dedicated plan to eradicate malaria. Hence, the Greek Anti-Malaria League ...

Cytolytic T lymphocyte-associated Ag-4 (CD152) is a negatively regulating molecule, which is primarily expressed on T cells following their activation. In this study, we have examined the role of CTLA-4 expression in experimental blood-stage malaria. Similar to human malaria, CTLA-4 is expressed on CD4(+) T cells of C57BL/6 mice after infection with Plasmodium berghei. A kinetic analysis reveal...

BACKGROUND AND OBJECTIVE Dihydroartemisinin-piperaquine (DhP) is a very cost effective anti-malarial drug. The aim of this study was to predict the budget impact of using DhP as a first- or second-line drug to treat uncomplicated malaria in children in Tanzania. METHODS A dynamic Markov decision model was developed based on clinical and epidemiological data to estimate annual cases of malaria...