Why use Buscopan during diagnostic upper gastrointestinal endoscopy? EDITOR,-In their audit of upper gastro-intestinal endoscopy (Gut 1995; 36: 462-7), Quine et al considered the issues surrounding the use of anticholinergic agents during upper gastrointestinal endoscopy. They found that although most procedures were performed without the use of either hyoscine butyl-bromide (Buscopan, Boehring...

Nimbidin the major bitter principle from oil of seeds of Azadirachta indica A. Juss was investigated for various pharmacological actions in a number animal models. On central nervous system it exhibited moderate sedative effect it did not show any significant cardiovascular effects in experimental animals. Autonomic pharmacological studies (in-vitro) revealed pronounced anticholinergic antihist...

Central anticholinergic syndrome (CAS) presents with central and/or peripheral neurological symptoms after exposure to medication. Pain management is a challenge for patients who have CAS and concurrent cancer-related pain. We present patient became lethargic unresponsive receiving butorphanol, persistent despite administration of an opioid antagonist. This case report the first suggest causal ...

PURPOSE The effects of an anticholinergic or antidiuretic agent as add-on therapy to an alpha-blocker for lower urinary tract symptoms (LUTS) according to a voiding diary in 3 days are unknown. We prospectively investigated the efficacy of an anticholinergic or antidiuretic agent as add-on therapy for nocturia in men previously treated with an alpha-blocker for LUTS. SUBJECTS AND METHODS Pati...

Objective: To investigate the relationship between anticholinergic load (ACL) and self-perceived general health in adults a medium-sized municipality southern Brazil. Methods: This cross-sectional study was based on 2015 data from All respondents aged 44 years or older who reported using drugs 2 weeks before interview were included (n = 662). The Anticholinergic Drug Scale used to measure ACL. ...