in traditional system of indian medicine, c.bonducella is widely used for its antipyretic, antiperiodic, anticonvulsive, and antiparalytic activities. for assessing anticonvulsant activity, pentylenetetrazole, maximal electro shock, strychnine- and picrotoxin-induced convulsions models were used. diazepam was used as a standard reference for all models except maximal electro shock model, wherei...

conclusions anti-tuberculosis drugs-induced hepatotoxicity caused treatment interruption in 5.5% of the patients with tuberculosis. the majority of the patients with dih were above fifty, and 50% the cases occurred during the first two weeks after treatment onset. physicians must carefully and closely monitor such patients. background hepatotoxicity is one of the most frequent adverse events th...

extract   until recent years pharmacological researches focused on pathogeneses and abnormality in organogenesis but now researchers are studying drugs physiological disorders in pregnancy. these studies are specially focused on mothers and fetus, regulatory mechanism of passing drugs through placenta and movement of drug' materials between barriers of milk and blood in the breast. also th...

introduction: since prescription is a way of communication between the pharmacist, physician and patient, inattention to its principles may result in mis-consumption or incomplete use of the medicine, drug interactions, and increased probable adverse effects. therefore, this research tried to investigate physicians' commitment to principles of prescription writing for outpatients insured by med...

In traditional system of Indian medicine, C.bonducella is widely used for its antipyretic, antiperiodic, anticonvulsive, and antiparalytic activities. For assessing anticonvulsant activity, pentylenetetrazole, maximal electro shock, strychnine- and picrotoxin-induced convulsions models were used. Diazepam was used as a standard reference for all models except maximal electro shock model, wh...