Achillea fragrantissima Forssk. (Family: Asteraceae) has been used as a natural remedy in the Arabian region for its antihyperglycemic activity. As result of intensive demand this plant folk medicinal uses, scarcity become problematic. This study explored methods that produce an efficient vitro culture protocol conservation well enhancement hypoglycemic A. cultures on Murashige and Skoog (MS) m...

Background: Oral contraceptive pills are commonly used in the treatment of PCOS; but, their influence on metabolic parameters is not well known. Metformin, a biguanide antihyperglycemic drug, has been shown to improve ovarian function and glucose metabolism in women with polycystic ovary syndrome (PCOS), but results concerning its effects

The current study aimed to evaluate the efficacy of simultaneous administration Zingiber officinale (ginger) and Cinnamomum cassia (cinnamon) extracts in mitigating testicular changes associated with diabetes mellitus rats investigate its molecular mode action. After induction using streptozotocin, 36 male were divided six groups namely control, diabetic, metformin-treated, cinnamon-treated, gi...

BACKGROUND Metformin is the first-line oral antihyperglycemic of choice for individuals with type 2 diabetes. Recent evidence supports a role for metformin in prostate cancer chemoprotection. However, whether metformin indeed influences prostate biology is unknown. We aimed to study the association between metformin and serum prostate-specific antigen (PSA) levels-the primary prostate cancer bi...

INTRODUCTION Previous research has demonstrated a correlation among patient preferences, dosing burden, and medication nonadherence, a well-recognized challenge in type 2 diabetes mellitus (T2DM). The objective of this study was to elicit preferences for alternative dosing regimens for oral antihyperglycemic therapies among patients with T2DM and to quantify differences in dosing preferences am...

BACKGROUND Hyperglycemia is a complicated condition accompanied with high incidence of infection and dyslipidemia. This study aimed to explore the phyto-constituents of Crataegus azarolus var. eu- azarolus Maire leaves, and to evaluate the therapeutic potentials particularly antimicrobial, antihyperglycemic and antihyperlipidemic of the extract and the isolated compound (3β-O-acetyl ursolic aci...

OBJECTIVE The purpose of this study was to examine the predictors of intensification of antihyperglycemic therapy in patients with type 2 diabetes; its impact on A1C, body weight, symptoms of anxiety/depression, and health status; and patient characteristics associated with improvement in A1C. RESEARCH DESIGN AND METHODS We analyzed survey, medical record, and health plan administrative data ...

The present study was carried out to investigate the antihyperglycemic effect of Oxytenanthera abyssinica leaf extract and fractions. Diabetes induced in rats by administering a single dose 150 mg/kg alloxan monohydrate. Single doses 100 200 methanol (Met-E), n-hexane fraction (nHex-F), ethyl-acetate (EA-F) (Met-F) were orally administered diabetic rats. Met-E Met-F selected at 400 mg/kg. plasm...