PURPOSE To investigate the concentration and bioavailability of ciprofloxacin and teicoplanin in the cornea. METHODS A biological assay was developed with corneal tissue used as a carrier for the antimicrobial. Concentration and biological activity were determined with a chemical assay and zone of inhibition (ZOI) around corneal samples with epithelial and endothelial surfaces in contact with...

OBJECTIVE Many dental diseases are attributable to biofilms. The screening of antimicrobial substances, in particular, requires a high sample throughput and a realistic model, the evaluation must be as quick and as simple as possible. For this purpose, a colorimetric assay of the tetrazolium salt XTT (sodium 3'-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic a...

Fresh leaves of Erigeron floribundus were obtained, and its ethanolic extract was assessed for antimicrobial, antioxidant-free radical scavenging activity as well phytochemical constituents. Hemolytic activities also screened to know whether the will lyse blood agar. Six pathogenic bacteria; gram-positive, Bacillus cereus, Clostridium species, Staphylococcus aureus, gram-negative: Klebsiella pn...

Background: Plant-derived Essential Oils (EOs) have shown remarkable antimicrobial activity against spoilage and pathogenic microorganisms isolated from food products. The objective of the current study was to determine in vitro antimicrobial effects of selected EOs against these microorganisms. Methods: Antimicrobial activity of EOs against food-borne and spoilage microorganisms was screened ...

Aims: The purpose is to study Pharmacognostical characteristics, Physicochemical evaluation, Phytochemical and Antimicrobial assay of Curcuma longa leaves extract. Methods Material: Different qualitative tests were performed confirmed the presence phytochemical compounds under consideration followed by quantitative analysis using sophisticated techniques such as spectrophotometric, Thin layer c...

The emergence of antibiotic resistant microorganism strains has become a critical concern in the treatment infectious diseases and makes search an alternative therapy must. study was designed to evaluate vitro antimicrobial activities Moringa peregrina (MP) leave (MPL) seed (MPS) extracts. Antimicrobial assays were performed using microplate growth inhibition assay against 11 multidrug-resistan...

Introduction. Duodenal ulcer in children is characterized by a significant prevalence, frequent development of serious complications and the need for large financial allocations implementation treatment programs. Antimicrobial peptides have an immunomodulatory function can be used as markers severity inflammatory process.Aim. To investigate concentration HNPs 1-3 LL-37 with duodenal ulcer.Metho...

PURPOSE To characterize the anatomy of the fruit and leaf and the presence of phytocompounds. To evaluate the antitumor and antimicrobial activity of ethanolic extract of Garcinia mangostana L. (mangosteen) cultivated in southeastern Brazil. METHODS Anatomical characterization and histochemical reactions were performed for structural identification and the presence of phytocompounds. Preparat...

BACKGROUND A novel series of 5-(substituted aldehyde)-7-methyl-3-oxo-N-phenyl-2-((3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methylene)-1,2,3,5-tetrahydroimidazo[1,2-a]pyrimidine-6-carboxamide analogues (1-24) was synthesized using the Biginelli condensation. RESULTS AND DISCUSSION The synthesized compounds were screened for their in vitro antimicrobial potential against Gram (positive and ...

Anguillospora longissima, isolated from root as endophytic freshwater hyphomycetes, was evaluated for its bioactivity (antibacterial potential) against five bacterial strains, namely, Gram-positive (Bacillus subtilis MTCC 121) and Gram-negative (Agrobacterium tumefaciens MTCC 609, Escherichia coli MTCC 40, Erwinia chrysanthemum, and Xanthomonas pseudomonas). Antimicrobial activity was assessed ...