Staphylococcus aureus is one of the most common causes of nosocomial infections. The purpose of this study was the synthesis and in vitro evaluation of antimicrobial activity of 10 new 3-oxazolidin-2-one analogues on 12 methicillin resistant S. aureus (MRSA) clinical isolates. S. aureus confirmation was achieved via catalase and coagulase test. Molecular characterization of MRSA was performed b...

objective(s) rapidly growing mycobacteria (rgm) are capable of producing diseases in humans. since mycobacteria vary in their susceptibility, precise identification is critical for adoption of correct drug therapy. the main aim of this study was molecular identification and evaluation of antimicrobial susceptibility pattern of iranian clinically isolated myocbacterium fortuitum. materials and m...

The aim of this study was to determine the prevalence of subclinical mastitis in dairy cows in Kosovo and the antimicrobial susceptibility of isolated bacteria. Six hundred and twenty four milk samples from individual quarters of 156 lactating cows were tested using California Mastitis Test (CMT) and the positive samples were further analysed using conventional methods for isolation of main mas...

BACKGROUND Bloodstream infections (BSIs) are the major cause of mortality in cancer patients. Molecular techniques are used for rapid diagnosis of BSI, allowing early therapy and improving survival. We aimed to establish whether real-time quantitative polymerase chain reaction (qPCR) could improve early diagnosis and therapy in paediatric cancer patients, and describe the predominant pathogens ...

OBJECTIVE To determine the frequency of capsular serotypes and the antimicrobial susceptibility of strains of Streptococcus pneumoniae, as well as to provide recommendations on the use of available vaccines and antimicrobial drugs. METHODS In this retrospective study, standard procedures were followed to identify, serotype, and determine bacterial susceptibility to penicillin, cefotaxime, and...

BACKGROUND AND OBJECTIVES Presence of methicillin and multidrug resistance has associated coagulase negative staphylococci (CNS) with high morbidity and mortality worldwide. The present study was carried out to study the susceptibility pattern of CNS to various antimicrobial agents and to determine the prevalence of CNS methicillin resistance in our hospital setting. MATERIALS AND METHODS A t...

Recurrent urinary tract infections are often re-infections; therefore, antimicrobial susceptibility test results from a previous episode may guide the empiric therapy in subsequent episodes. This analysis provides predictive values of the antimicrobial susceptibility of previous Escherichia coli isolates for the treatment of re-infections in routine clinical practice. If resistance to ampicilli...

The Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) Program is a global, longitudinal antimicrobial resistance surveillance network of greater than 100 medical centers worldwide monitoring the susceptibility of bacterial pathogens to carbapenems and other broad-spectrum agents. Between 1999 and 2002, 15 US medical centers referred up to 200 nonduplicate isolates from clinic...

The breakpoints used to interpret antimicrobial susceptibility tests should be carefully determined initially, using microbiological, pharmacokinetic, pharmacodynamic, and clinical data, and then reevaluated periodically as changes in bacterial resistance, susceptibility test methods, or antibiotic formulations occur. Throughout the world, different governmental agencies and professional organi...

Infections caused by Chlamydia spp are an important cause of human disease, and the accuracy and reproducibility of antimicrobial susceptibility tests for these bacteria could have considerable clinical implications. We have developed a reverse transcriptase PCR (RT-PCR) based method to determine the antibiotic susceptibility of Chlamydia spp., and compared this with conventional tests using im...