New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. The structures of the obtained compounds were elucidated by IR and NMR spectra and also analytical elemental analysis. In the next step, the above mention...

New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. The structures of the obtained compounds were elucidated by IR and NMR spectra and also analytical elemental analysis. In the next step, the above mention...

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...

Plant materials were used for the treatment of malignant diseases for centuries. Various studies on plant extract which have a suitable history of use in folklore for the treatment of cancer had often resulted in the isolation of principles with anti-tumour activity. In the present study, the anti-proliferative effect of acetone and methanol bark extracts of Adenanthera pavonina on three cancer...

Comparison of the effectiveness of antioxidant activity of three thiol compounds, D-penicillamine, reduced L-glutathione, and 1,4-dithioerythritol, expressed as a radical-scavenging capacity based on the two independent methods, namely a decolorization 2,2'-azinobis[3-ethylbenzothiazoline-6-sulfonic acid] assay and a rotational viscometry, is reported. Particular concern was focused on the test...

The essential oil (EO) obtained by hydrodistillation from Teucrium polium L. was analyzed by gas chromatography and gas chromatography mass spectrometry (GC/MS). Antioxidant activity was evaluated through DPPH assay and Beta-carotene/linoleic acid assay. Twenty one components were identified representing (90.4%) of the EO. Main constituents of the essential oil were found as Spathulenol (15.06%...

Objective: The primary objective was to study the in vitro antioxidant and anticancer evaluation of novel 5-benzylidene substituted rhodanine derivatives molecular docking studies most active compounds with 3 different targets. Methods: Antioxidant potential were studied by DPPH assay, done MTT assay Computational using various softwares such as ACD Lab Chemsketch 12.0, molinspiration Discovery...

Neurodegenerative diseases like Parkinson’s disease (PD),Amyotrophic Lateral Sclerosis (ALS) and Schizophrenia are a group of illness with diverse clinical importance and etiologies. Oxidative stress in which production of highly reactive oxygen species (ROS) and reactive nitrogen species (RNS) overwhelms antioxidant defences, is a feature of many neurological diseases. Lycopene, the most poten...