نتایج جستجو برای: antiproliferative activity

تعداد نتایج: 1139196  

2010
Stefan Schulz Jeroen S. Dickschat Brigitte Kunze Irene Wagner-Dobler Randi Diestel Florenz Sasse

The antiproliferative activity of 52 volatile compounds released from bacteria was investigated in agar diffusion assays against medically important microorganisms and mouse fibroblasts. Furthermore, the activity of these compounds to interfere with the quorum-sensing-systems was tested with two different reporter strains. While some of the compounds specific to certain bacteria showed some act...

Journal: :Plant foods for human nutrition 2009
Buk-Gu Heo Sang-Uk Chon Yun-Jum Park Jong-Hyang Bae Su-Min Park Yong-Seo Park Hong-Gi Jang Shela Gorinstein

This study was conducted to determine the antiproliferative activity of 24 Korean wild vegetables. The methanol extracts of these wild vegetables were used against lung, breast, colon and gastric cancer cells, and the results were assessed by MTT assay. It was found that at the extract concentration of 400 mgL(-1) 14 plants exercised antiproliferative activity over 80% against the lung cancer c...

Journal: :The Journal of Cell Biology 1990
D Muir S Varon M Manthorpe

In healthy adult peripheral nerve, Schwann cells are believed to be generally quiescent. Similarly, cultures of isolated rat sciatic nerve Schwann cells hardly proliferate in serum-supplemented medium. The possibility that Schwann cells negatively regulate their own proliferation was supported by the demonstration that conditioned media from Schwann cell cultures inhibited the proliferation of ...

2011
Victoria C Smith Laura A T Cleghorn Andrew Woodland Daniel Spinks Irene Hallyburton Iain T Collie N Yi Mok Suzanne Norval Ruth Brenk Alan H Fairlamb Julie A Frearson Kevin D Read Ian H Gilbert Paul G Wyatt

Screening of the Sigma-Aldrich Library of Pharmacologically Active Compounds (LOPAC) against cultured Trypanosoma brucei, the causative agent of African sleeping sickness, resulted in the identification of a number of compounds with selective antiproliferative activity over mammalian cells. These included (+)-(1R,2R)-U50488, a weak opioid agonist with an EC(50) value of 59 nM as determined in o...

Journal: :Asia Pacific journal of clinical nutrition 2007
Guidong Huang Xianfeng Zhong Yusheng Cao Yan Chen

Conjugated linoleic acid (CLA) reduces body fat reserves, and reduces atherogenesis and type II diabetes in animal experiments. It has been reported that CLA have isomeric-specificity, such as c9, t11 CLA with anticancer activity. The antiproliferative effects of two isomers of CLA (c9, t11-CLA, t9, t11-CLA) and their mixture on the human colon adenocarcinoma cell line Caco-2 were investigated ...

2012
Murat Kizaibek Ruxandra Popescu Sonja Prinz Halmurat Upur Judith Singhuber Martin Zehl Brigitte Kopp

Abnormal Savda Munziq (ASMq) is a herbal preparation used in Traditional Uighur Medicine for the treatment and prevention of diabetes, cardiovascular diseases, chronic asthma and cancer. The recommended dose of this decoction for cancer patients is 500 mL administered orally three times a day. Our approach aimed at reducing the high amount of fluid intake required by fractionation of ASMq guide...

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