Micronized powders are of interest in many industrial fields; pharmaceuticals, catalysts, pigments, and biopolymers, for example, are some categories of products that can be used as micro-sized particles. Traditional techniques used to produce micronic powders are based on high-temperature reactions that require high energies, on jet milling that is characterized by low efficiencies and mechani...

The utilization of SCFs for the processing of several products has attracted considerable interest in recent years as an emerging “green” technology. Particle formation using SCFs can be carried out according to several different techniques, including antisolvent techniques such as the gas-antisolvent (GAS) process. The potential advantages of the GAS crystallization process lies in the possibi...

Crystallization processes in the pharmaceutical industry are usually designed to obtain crystals with controlled size, shape, purity, and polymorphic form. Knowledge of the process conditions required to fabricate crystals with controlled characteristics is critical during process development. In this work, continuous crystallization of Ketoconazole, Flufenamic Acid, and L-Glutamic Acid in a no...

Abstract: Background: Phytosome is a novel technique introduced by Indena that combines standardised herbal extract and phospholipid in preferably equal ratio to provide better absorption enhancing bioavailability. Purpose: The objective of proposed study prepare, optimise characterize phytosomes Murraya koenigii (Linn.) Spreng improve its antidiabetic properties. Materials Methods: Antisolvent...

Differences in physical and chemical properties between polymorphic compounds (e.g. solubility, dissolution rate, chemical reactivity, resistance to degradation, bioavailability) are highly significant for the pharmaceutical industry, which requires effective methods to control polymorphism of organic crystals [1, 2]. In particular, to improve the functionality such as solubility or bioavailabi...