نتایج جستجو برای: antitubercular activity

تعداد نتایج: 1136222  

2008
S.K. Singh Z. Ahmad D.K. Pandey V. Gupta S. Naaz

Isoniazid (INH) is a first-line antitubercular drug. We report a case of a patient who developed a pleural effusion 2 months after starting antitubercular treatment for spinal tuberculosis. Isoniazid was found to be the culprit and its discontinuation caused subsidence of the effusion.

Journal: :Antimicrobial agents and chemotherapy 2014
Maria V Papadopoulou William D Bloomer Howard S Rosenzweig Alexander Arena Francisco Arrieta Joseph C J Rebolledo Diane K Smith

Twenty-three 3-nitrotriazole-based and 2-nitroimidazole-based amides and sulfonamides were screened for antitubercular (anti-TB) activity in aerobic Mycobacterium tuberculosis H37Rv by using the BacTiter-Glo (BTG) microbial cell viability assay. In general, 3-nitrotriazole-based sulfonamides demonstrated anti-TB activity, whereas 3-nitrotriazole-based amides and 2-nitroimidazole-based amides an...

2012
Karina Andrade de Prince Renata Sordi Fernando Rogério Pavan Adolfo Carlos Barreto Santos Angela R. Araujo Sergio R.A. Leite Clarice Q. F. Leite

Our purpose was to determine the anti-Mycobacterium tuberculosis activity of the metabolites produced by the endophitic fungus Phomopsis stipata (Lib.) B. Sutton, (Diaporthaceae), cultivated in different media. The antimycobacterial activity was assessed through the Resazurin Microtiter Assay (REMA) and the cytotoxicity test performed on macrophage cell line. The extracts derived from fungi gro...

Journal: :International Journal of Pharmacy and Pharmaceutical Sciences 2016

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