نتایج جستجو برای: antivirulence agents
تعداد نتایج: 360788 فیلتر نتایج به سال:
Blue light emitting diodes enhance the antivirulence effects of Curcumin against Helicobacter pylori
Complex oligosaccharides from human milk (HMO) possess an antimicrobial activity and can promote the growth of bifidobacteria such as Bifidobacterium bifidum and Bifidobacterium longum subsp. infantis. In addition, fermentation of carbohydrates by bifidobacteria can result in the production of metabolites presenting an antivirulence effect on several pathogenic bacteria. Whey is rich in complex...
An overview of investigational antibiotics highlights that antimicrobial drug development is slower than the emergence and spread of resistant strains. In the last three decades only two antibiotics belonging to truly new classes have been introduced into the market, i.e. linezolid and daptomycin. This situation is fostering a huge amount of research aimed at the development of novel molecules ...
LcrF (VirF), a transcription factor in the multiple adaptational response (MAR) family, regulates expression of the Yersinia type III secretion system (T3SS). Yersinia pseudotuberculosis lcrF-null mutants showed attenuated virulence in tissue culture and animal models of infection. Targeting of LcrF offers a novel, antivirulence strategy for preventing Yersinia infection. A small molecule libra...
The endophytic fungus Penicillium restrictum was isolated from the stems of a milk thistle (Silybum marianum) plant. In culture, the fungus produced distinct red guttates, which have been virtually uninvestigated, particularly from the standpoint of chemistry. Hence, this study examined the chemical mycology of P. restrictum and, in doing so, uncovered a series of both known and new polyhydroxy...
conclusions potato peels were proved to be potentially useful substrates for biosurfactant production by b. pumilus dsvp18. the strain possessed a unique property to reduce surface tension of the media from 72 to 28.7 mn/m. in addition, it showed a stable surface activity over a wide range of temperatures, ph, and saline conditions and had strong antimicrobial activity. this potential of the id...
treatment of tuberculosis was an obstacle for ages. in spite of good drugs, the disease is not under control. thus, the need for more drugs existed. searching for a new drug demands much investment on the time, money and human resources. there are many drugs with antitubercular action that are discovered and explored in the last century. the most common drug, isoniazid, is now a frontrunner ant...
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