Ascending aortic aneurysm is a rare cause of superior vena cava syndrome. Herein, we describe a case of superior vena cava syndrome caused by a chronic dissecting aortic aneurysm after aortic valve replacement. A successful replacement of the aortic root and ascending aorta led to an improvement of edema of the face and bilateral upper limbs caused by superior vena cava syndrome.

Schmit BM, Yang P, Fu C, DeSart K, Berceli SA, Jiang Z. Hypertension overrides the protective effect of female hormones on the development of aortic aneurysm secondary to Alk5 deficiency via ERK activation. Am J Physiol Heart Circ Physiol 308: H115–H125, 2015. First published November 11, 2014; doi:10.1152/ajpheart.00521.2014.— The prevalence of aortic aneurysm is five times higher in men than ...

A 57-year-old man was referred for exertional chest pain and a mediastinal mass. Computed tomographic angiography (CTA) revealed a huge aneurysm arising from the left sinus of Valsalva (Figure 1, Video I in the online-only Data Supplement). The opening of aneurysm was 18 mm in its largest diameter. Because the left coronary arteries were stretched and narrowed, the chest pain was considered to ...

A 57-year-old man was referred for exertional chest pain and a mediastinal mass. Computed tomographic angiography (CTA) revealed a huge aneurysm arising from the left sinus of Valsalva (Figure 1, Video I in the online-only Data Supplement). The opening of aneurysm was 18 mm in its largest diameter. Because the left coronary arteries were stretched and narrowed, the chest pain was considered to ...

A case of Turner's syndrome is described associated with bicuspid aortic stenosis and fatal rupture of a thoracic dissecting aortic aneurysm. Histology of the aneurysm showed severe cystic medial necrosis. This association has not been previously described in the absence of coarctation. In view of the possibility of surgical repair, dissecting aortic aneurysm should be considered in all patient...

Chronic-contained aortic aneurysm rupture with vertebral erosion is a rare entity with fatal complications. Multidetector computed tomography (CT) angiography is an important diagnostic method for the evaluation of the aortic aneurysms, their complications, and also the relationship between aneurysm and branching vessels and adjacent structures. We present the multidetector CT angiography findi...

The purpose of this study was to profile altered patterns of gene expression that characterize abdominal aortic aneurysm and to compare these patterns between different conditions, unruptured (URA) and ruptured (RA). Full-thickness aortic wall tissues were obtained from patients during surgical repair of abdominal aortic aneurysm, including unruptured (n=29) and ruptured (n=11). RNA, protein an...

Left recurrent laryngeal nerve palsy rarely results from cardiac disease. We present 2 cases of left recurrent laryngeal nerve palsy caused by thoracic saccular aortic aneurysms. One patient suffered an aortic aneurysm rupture one month after the advent of hoarseness, necessitating emergency surgery with aortic arch replacement. The other patient underwent elective aortic arch replacement surge...

BACKGROUND Ultrasmall superparamagnetic particles of iron oxide (USPIO) detect cellular inflammation on magnetic resonance imaging (MRI). In patients with abdominal aortic aneurysm, we assessed whether USPIO-enhanced MRI can predict aneurysm growth rates and clinical outcomes. METHODS In a prospective multicenter open-label cohort study, 342 patients with abdominal aortic aneurysm (diameter ≥...

Previous data suggest women are at increased risk of death from aortic dissection. Therefore, we analyzed data from the GenTAC registry, the NIH-sponsored program that collects information about individuals with genetically triggered thoracic aortic aneurysms and cardiovascular conditions. We performed cross-sectional analyses in adults with Marfan syndrome (MFS), familial thoracic aortic aneur...