BACKGROUND Children with obstructive sleep apnea (OSA) have a higher rate of adverse post-extubation respiratory events, such as laryngospasm, upper airway obstruction, apnea, desaturation and/or need for re-intubation. They are overly sensitive to sedatives and narcotics. Although the etiology of OSA is primarily obstruction (mechanical or neuromuscular), a central element may contribute to OS...

to determine the role of blood transfusion protocols on retinopathy of prematurity (rop), a prospective cohort study on 57 premature infants under 1501 grams birth weight was performed. fourteen day-old infants were divided into two groups randomly. infants in group 1 (n=27) received packed red blood cell transfusion only if specific medical signs were met and their hematocrit level was under 3...

IMPORTANCE Advantages of caffeine for apnea of prematurity have prompted clinicians to use it prophylactically even before apnea. OBJECTIVE To determine the effect of early initiation of caffeine therapy on neonatal outcomes in very preterm infants born in Canada. DESIGN, SETTING, AND PARTICIPANTS A retrospective cohort study was conducted. Patients included preterm neonates born at less th...

STUDY OBJECTIVES To evaluate prospectively the ability of two equations that we previously derived to predict maintenance theophylline dosages that provide a serum theophylline concentration (STC) of 8 micrograms/ml, the midtherapeutic range for treating apnea of prematurity; and to determine the number of further dosage adjustments and STC determinations required to achieve the target concentr...

Introduction: The prevalence of retinopathy of prematurity is expected to increase along with the developing of premature infants’ care and better prognosis of these infants. The aim of this study was to evaluate the prevalence of retinopathy of prematurity in preterm infants. Methods: According to this cross-sectional study, one same ophthalmologist examined the eyes of all the babies at 4 we...

AIMS To evaluate parental compliance with home cardiorespiratory monitoring of premature infants with apnoea, siblings of infants who died of sudden infant death syndrome (SIDS), and infants with an apparent life threatening event (ALTE), during the first month of use. METHODS A retrospective review of the first month's recordings was conducted on 39 premature infants with apnoea, 13 siblings...

OBJECTIVE To determine effects of theophylline therapy for recurrent apnoea of prematurity and abnormal early (within the first 24 hours) cranial ultrasound abnormalities on protective neck turning response in preterm infants. DESIGN A cross sectional descriptive study. SETTING The Neonatal Unit of Hammersmith Hospital, London over a period of four months (February to May 1987) and the babi...

Caffeine is a first-line option for the neonatal intensive care management of apnea prematurity (AOP) in preterm infants. This first study literature to evaluate cost effectiveness off-label high dose (HD) caffeine versus approved standard lower (LD) treatment AOP neonates. From hospital perspective Hamad Medical Corporation (HMC) Qatar, this was cost-effectiveness analysis based on conventiona...