نتایج جستجو برای: apolipoproteins e

تعداد نتایج: 1023956  

Journal: :Journal of lipid research 1999
C Khoo H Campos H Judge F M Sacks

Apolipoproteins E and C-III are modulators of lipoprotein metabolism that could affect development of atherosclerosis. The prevalence in plasma of apoB-containing particles (LpB) that contain either apoE or apoC-III, both or neither, and the effect of estrogen on these lipoproteins are unknown. The LpB particle system, defined by the presence or absence of apoE or C-III, was studied in 13 normo...

Journal: :Clinical chemistry 1997
G de Bellis G Salani S Panigone F Betti L Invernizzi M Luzzana

We present the genotyping of apolipoprotein (apo) E by means of restriction fragment analysis of amplified genomic DNA by high-performance capillary electrophoresis and a replaceable non-gel-sieving matrix. This procedure streamlines the genotyping of apo E in large-scale population studies because of the automation and speed of capillary electrophoresis.

Journal: :The journals of gerontology. Series B, Psychological sciences and social sciences 2005
David Bunce Miia Kivipelto Ake Wahlin

Recognition of dated and contemporary famous faces, short-term memory, and visuospatial abilities were investigated in adults aged 75 years and older as a function of apolipoprotein E (APOE) genotype, epsilon4 or not epsilon4, and whether participants recorded normal or low levels of B vitamins. No associations between B vitamins and APOE were identified in respect to short-term memory or visuo...

Journal: :The Journal of antibiotics 2000
M Yanai M Suzuki K Kawamura N Oshida S Hiramoto O Yasuda A Shingai T Suguro

Analogs of N-4909 (1), which had a stimulating activity for apolipoprotein E (apo E) secretion in Human hepatoma Hep G2 cells, were prepared and their activities examined. Cyclic analogs which had different kinds of amino acids or different number of amino acids from N-4909 (1) showed less effect on apo E secretion from Hep G2 cells. The length of acyl chain was found to be an important factor ...

2009
Andrew D. Frutkin Goro Otsuka April Stempien-Otero Casilde Sesti Liang Du Mia Jaffe Helén L. Dichek Caroline J. Pennington Dylan R. Edwards Madeline Nieves-Cintrón Daniel Minter Michael Preusch Jie Hong Hu Julien C. Marie David A. Dichek

Journal: :Journal of Alzheimer's disease : JAD 2006
June Kinoshita Anne Fagan David Ewbank Michael Marlatt Patricia Heyn Suzanne de la Monte Nancy Emerson Lombardo

1Note: The transcript has been edited for clarity and accuracy. on alternatives to factor analysis for defining insulin resistance syndrome (IRS). I will be using an alternative to standard meta-analysis that I developed for studying Apolipoprotein E (ApoE), AD, and mortality. Perhaps I can start with a question. There is a huge literature correlating ApoE genotype and anything else you can thi...

Journal: :Journal of Alzheimer's disease : JAD 2014
Wasim Khan Vincent Giampietro Cedric Ginestet Flavio Dell'Acqua David Bouls Steven Newhouse Richard Dobson Tobias Banaschewski Gareth J Barker Arun L W Bokde Christian Büchel Patricia Conrod Herta Flor Vincent Frouin Hugh Garavan Penny Gowland Anreas Heinz Bernd Ittermann Hervé Lemaître Frauke Nees Tomas Paus Zdenka Pausova Marcella Rietschel Michael N Smolka Andreas Ströhle Jean Gallinat Eric Westman Gunther Schumann Simon Lovestone Andrew Simmons

Alleles of the apolipoprotein E (ApoE) gene are known to modulate the genetic risk for developing late-onset Alzheimer's disease (AD) and have been associated with hippocampal volume differences in AD. However, the effect of these alleles on hippocampal volume in younger subjects has yet to be clearly established. Using a large cohort of more than 1,400 adolescents, this study found no hippocam...

Journal: :The Journal of biological chemistry 2003
Monica H Farkas Larry L Swift Alyssa H Hasty MacRae F Linton Sergio Fazio

Internalization of apoE-containing very low density protein (VLDL) by hepatocytes in vivo and in vitro leads to apoE recycling and resecretion. Because of the role of apoE in VLDL metabolism, apoE recycling may influence lipoprotein assembly or remnant uptake. However, apoE is also a HDL protein, and apoE recycling may be related to reverse cholesterol transport. To investigate apoE recycling, ...

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2003

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