helicobacter pylori infection is one of the most common human infections which have been associated with many upper gasterointestinal complications. different treatment regimens for helicobacter pylori eradication have been used. one of these regimes is the quadruple therapy regimen which metronidazole is one of the medications. in recent years several reports on h. pylori resistance to this an...

Heavy metals are stable environmental contaminants, causing various alterations in target tissues. Garlic has some beneficial effect in preventing heavy metal induced various alteration. The objective was to investigate the possible protective role of fresh aqueous homogenate of garlic on hematology, erythrocyte antioxidant defense system in male albino rats treated with NiSO4 and K2Cr2O7. Rats...

abstract introduction the main function of the fibrinolytic system is to dissolve fibrin clots in circulation. this system is composed of inactive precursor plasminogen which can be converted into plasmin by the proteolytic enzymes like tissue-type plasminogen activator (tpa). fibrinolytic properties can be found in a variety of medicine plants and they could effectively prevent cardiovascular ...

OBJECTIVES Comparative hypoglycemic and hypolipidaemic activity of garlic (ethanol) extract and metformin was the aim of the study in 24 normal and diabetic rabbits. MATERIAL AND METHODS In group A of 12 rabbits, the influence of different doses (250, 300 and 350 mg/kg body weight) of garlic extract was evaluated, six of them were kept normal, while six were caused to be diabetic with alloxan...

BACKGROUND Garlic (Allium sativum) has been shown to have important benefits in individuals at high cardiovascular risk. The aim of the present study was to evaluate the effects of the administration of aged garlic extract (AGE) on the risk factors that constitute the cluster of metabolic syndrome (MS). METHODS AND DESIGN Double-blind, crossover, randomized, placebo-controlled clinical trial ...

Intravenous administration of garlic extract (25.9 mg/kg body weight), significantly increases urinary output in dogs, whjch was also found to be dose dependent. The pH of urine was not altered after the administration of garlic extract. Effect of intravenous administration of Furosemide (1.0 mg/kg b. wt.) was also observed for control comparison. It was found that the garlic in high doses (54....

objective in previous studies, the relaxant, anticholinergic (functional antagonism), antihistaminic and its stimulatory effects on b-adrenoceptors of nigella sativa have been demonstrated on guinea pig tracheal chains. in the present study, the relaxant effects of hydro-ethanolic, macerated aqueous (ma) and lipid-free macerated aqueous (lfma) extract of nigella sativa on tracheal chains of gui...

garlic is known as a potent spice and a medicinal herb with broad therapeutic properties ranging from antibacterial to anticancer and anticoagulant. our previous studies have shown some immunoregulatory effects for aged garlic extract, suggesting a key role for 14-kd glycoprotein of garlic in shifting the cytokine pattern to t helper-1. in present study, we investigated the effect of 1, 2, and ...

BACKGROUND Garlic is one of the medicinal plants which has showed beneficial effects on atherosclerosis risk factors. The liver X receptor α (LXRα) is an important regulator of cholesterol, triglyceride and glucose homeostasis that belongs to the nuclear receptor superfamily. In this study we investigated the effect of garlic on lipid profile, glucose as well as LXRα expression in intestine and...

The sulfurous acid ester, trans-sulfurous acid allyl ester 3-allylsulfanyl-allyl ester 8, along with two known thiosulfinates was isolated from the aqueous ethanol extract of garlic (Allium sativum). The chemical structure of 8 was determined on the basis of spectroscopic data including high resolution mass and two-dimensional NMR techniques. All of these compounds induced methemoglobin formati...