نتایج جستجو برای: arrhythmogenic right ventricular dysplasia

تعداد نتایج: 433082  

2012
Daniel H Katz Moneal Shah Ellen Cummings Jie J Cao

Background Right ventricular (RV) regional wall characteristics are important in CMR evaluation for arrhythmogenic RV dysplasia (ARVD). While some features are well defined, others are of uncertain clinical significance, due in part, to the high prevalence of RV wall motion variants found in normal subjects. In this study we performed a retrospective review of RV free wall characteristics in a ...

Journal: :Journal of cardiovascular electrophysiology 2010
Elena Arbelo Mark E Josephson

Arrhythmogenic right ventricular dysplasia (ARVD) is a genetically determined myocardial disease characterized by fibrofatty replacement of the right ventricular wall. Ventricular tachyarrhythmias can be seen in the early stages of the disease, which is one of the most important causes of sudden death in young healthy individuals. Radiofrequency (RF) catheter ablation is an option for the treat...

2015
Johnson Francis Narayanan Namboodiri

Ventricular arrhythmias due to ARVD and right ventricular outflow tract arrhythmia (RVOTA) share the same left bundle branch block pattern with inferior axis on the ECG. The former has a more malignant course while the latter has a better prognosis and is more amenable to radiofrequency catheter ablation. Hence differentiating them is of utmost clinical importance in the management of these pat...

Journal: :Soudni lekarstvi 2014
Takeshi Kondo

Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is characterized by progressive fatty and fibrous replacement. A female in her 70s, suddenly found in cardiopulmonary arrest. The heart weighed 452 g and yellow discoloration was observed. Histological examination revealed the replacement of the right ventricular myocardium by adipose tissue and fibrosis. The cause of death was ...

2015
Kristin McLeod Jørg Saberniak Kristina Haugaa

Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterized by fatty and fibrotic replacement of cardiac tissue, which ultimately affects the structure, function and electrical propagation of the ventricles. Diagnosis of ARVC is challenging and is currently guided by the 2010 Task force criteria (2010TFC), which includes criteria identified fro...

Journal: :Journal of the American College of Cardiology 2014
David J Wilber

Percutaneous epicardial access, introduced by Sosa et al. (1) in the mid-1990s, provided an important diagnostic and therapeutic approach to the recognition and management of scar-related epicardial ventricular tachycardia (VT). Since that time, the need for epicardial ablation has been reported in 10% to 15% of patients with ischemic cardiomyopathy (ICM) (2–4), 25% to 50% of patients with noni...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2006
Prince J Kannankeril Brett M Mitchell Sanjeewa A Goonasekera Mihail G Chelu Wei Zhang Subeena Sood Debra L Kearney Cristina I Danila Mariella De Biasi Xander H T Wehrens Robia G Pautler Dan M Roden George E Taffet Robert T Dirksen Mark E Anderson Susan L Hamilton

Mutations in the cardiac ryanodine receptor 2 (RyR2) have been associated with catecholaminergic polymorphic ventricular tachycardia and a form of arrhythmogenic right ventricular dysplasia. To study the relationship between RyR2 function and these phenotypes, we developed knockin mice with the human disease-associated RyR2 mutation R176Q. Histologic analysis of hearts from RyR2(R176Q/+) mice r...

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