As humans age, degenerative changes in the arterial structure gradually progress and result in the stiffening of the arteries, which is called arteriosclerosis. Arterial stiffness is now an established risk factor of cardiovascular disease (CVD). This stiffening has adverse effects for both the general population as well as for patients with CVD. Measurements of pulse wave velocity and pulse wa...

Arterial stiffness is a growing epidemic associated with increased risk of cardiovascular events, dementia, and death. Decreased compliance of the central vasculature alters arterial pressure and flow dynamics and impacts cardiac performance and coronary perfusion. This article reviews the structural, cellular, and genetic contributors to arterial stiffness, including the roles of the scaffoldi...

The purpose of this study was to evaluate whether arterial stiffness was different in aerobically trained elite athletes than in anaerobically or resistance trained elite athletes. The cohort comprised 36 healthy male volunteers, aged between 17 and 32 years. All subjects were basketball players (n=10), weightlifters (n=11) or sedentary controls (n=15). The Pulse Trace System (Micro Medical Ltd...

The increase of arterial stiffness has been to have a significant impact on predicting mortality in end-stage renal disease patients. Pulse wave velocity (PWV) is a noninvasive, reliable parameter of regional arterial stiffness that integrates the vascular geometry and arterial wall intrinsic elasticity and is capable of predicting cardiovascular mortality in this patient population. Neverthele...

Arterial stiffening characterizes ageing and several diseases related to increased cardiovascular (CV) risk such as the metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), hypertension, obesity and smoking. Several studies have shown that arterial stiffness is a strong, independent predictor of CV morbidity and mortality risk in such patient populations. Lifestyle measures and drugs fre...

Background. It was established that the prevalence of reduced bone mineral density is significantly higher among patients with arterial hypertension compared to healthy subjects. The purpose research study stiffness and central aortic pressure in women combined osteoporosis. Materials methods. 88 postmenopausal (average age 62.7±3.8 years) were included study, which 35 osteoporosis (OP) accordi...

[4] . It can also be affected by atherosclerotic risk factors such as smoking, alcohol consumption, hypercholesterolemia, hypothyroidism and older age [5] . Furthermore, some medications such as antihypertensive treatment including angiotensin-converting enzyme inhibitors, angiotensin receptor blocker, and statins used may influence arterial stiffness parameters [6] . However, the authors of th...

Arterial stiffness has been proposed as an indicator of vascular aging. We aimed to examine this concept by analyzing associations of arterial stiffness with age, subjective and objective measures of physical functioning, and self-reported functional limitation. We measured aortic pulse wave velocity by applanation tonometry among 5392 men and women aged 55 to 78 years. Arterial stiffness was s...

Arterial stiffness is an independent risk factor for fatal and non-fatal cardiovascular events, such as systolic hypertension, coronary artery disease, stroke, and heart failure. Moreover it reflects arterial aging which in many cases does not coincide with chronological aging, a fact that is in large attributed to genetic factors. In addition to genetic factors, microRNAs (miRNAs) seem to larg...

OBJECTIVES We sought to compare left ventricular (LV) systolic stiffness and contractility in normal subjects, hypertensive patients without heart failure, and patients with heart failure and preserved ejection fraction (HFpEF) and to determine whether LV systolic stiffness or myocardial contractility is associated with the rate of mortality in patients with HFpEF. BACKGROUND Arterial load is...