We use confocal microscopy to study the compressibility of a random-close-packed sample of colloidal particles. To do this, we introduce an algorithm to estimate the size of each particle. Taking into account their sizes, we compute the compressibility of the sample as a function of wave vector q, and find that this compressibility vanishes linearly as q→0, showing that the packing structure is...

Mesenchymal stem cells (MSCs) have been reported to secrete a variety of cytokines and growth factors acting as trophic suppliers, but little is known regarding the effects of conditioned medium (CM) of MSCs isolated from femurs and tibias of mouse on the artificial activation of mouse oocytes and on the developmental competence of the parthenotes. In the current study, we investigated the effe...

It has been reported that WIN55212-2, a prototypic aminoalkylindole, has higher affinity for CB(2) than for CB(1). To explain the selectivity of WIN55212-2 for CB(2), molecular modeling studies were performed to probe the interacting sites between WIN55212-2 and cannabinoid receptors. In TMH5 the position 5.46 is a Phe in CB(2) versus a Val in CB(1). Docking of WIN55212-2 into the models of CB(...

In the background of rapid development artificial intelligence, big data, IoT, 5G/6G, and other technologies, electrochemical sensors pose higher requirements for high-throughput detection. this study, we developed a workstation with up to 10 channels, which supports both parallel signal stimulation online analysis functions. The platform was wired highly integrated Bluetooth chip used wireless...

BACKGROUND Type-1 cannabinoid receptors (CB(1)R) are enriched in the hypothalamus, particularly in the ventromedial hypothalamic nucleus (VMH) that participates in homeostatic and behavioral functions including food intake. Although CB(1)R activation modulates excitatory and inhibitory synaptic transmission in the brain, CB(1)R contribution to the molecular architecture of the excitatory and in...

Exploring the role of cannabinoid CB(2) receptors in the brain, we present evidence of CB(2) receptor molecular and functional interaction with cannabinoid CB(1) receptors. Using biophysical and biochemical approaches, we discovered that CB(2) receptors can form heteromers with CB(1) receptors in transfected neuronal cells and in rat brain pineal gland, nucleus accumbens, and globus pallidus. W...

Centering theory (CT) has been mostly discussed from the point of view of interpretation rather than generation, and research has tended to concentrate on problems of anaphora resolution. This paper examines how centering could fit into the generation task, separating out components of the theory which are concerned with planning and lexical choice. We argue that it is a mistake to define a tot...

In this paper, natural heat convection inside square and equilateral triangular cavities was studied using a meshless method based on collocation local radial basis function (RBF). The nanofluids used were Cu-water or -water mixture with nanoparticle volume fractions range of . A system continuity, momentum, energy partial differential equations in modeling the flow temperature behavior fluids....

PURPOSE This study examined whether heat strain during low states of chemical and biological protection (CB(low)) impacted tolerance time (TT) after transition to a high state of protection (CB(high)) and whether vents in the uniform reduced heat strain during CB(low) and increased TT. METHODS There were eight men who walked at 35 degrees C in CB(low), and then transitioned to CB(high). Subje...

BACKGROUND The cell type(s) mediating the maternal influence on allergic disease in children remain unclear. We set out to define the relationship between maternal allergy and frequencies of cord blood (CB) basophils, and plasmacytoid dendritic cells (pDCs); to characterize surface-bound IgE and FcεRI expressions on these cells; and to investigate the association between maternal and CB serum I...