an important concern in rock mechanics is non-homogeneity as joints or fault. this noticeable feature of failures in rock is appearance of slip surfaces or shear bands, the characteristics of that are associated with deformation being concentrated in a narrow zones and the surrounding material remaining intact. adopting the joints as fractures, fractures are well known for their effects on the ...

background: n-terminal pro-brain natriuretic peptide (nt-probnp) is a sensitive biomarker for the detection of asymptomatic left ventricular (lv) dysfunction. since β-thalassemia major patients suffer from early diastolic dysfunction due to iron deposition of chronic blood transfusion, we tried to evaluate the correlation between the serum nt-probnp level and the severity of lv diastolic dysfun...

objective: this study aimed to compare the effect of using casein phosphopeptide – amorphous calcium phosphate (cpp-acp) paste, remin-pro and fluoride varnish on remineralization of enamel lesions. methods: in this experimental-in vitro study, 60 intact premolars and molars were used and flat enamel surfaces were prepared. the specimens were divided into 6 groups (n=10). after primary diagnoden...

objective(s): yu-ping-feng-san (ypfs) is a classical traditional chinese medicine that is widely used for treatment of the diseases in respiratory systems, including chronic obstructive pulmonary disease (copd) recognized as chronic inflammatory disease. however, the molecular mechanism remains unclear. here we detected the factors involved in transforming growth factor beta 1 (tgf-β1)/smad2 si...

Gamma-glutamyltranspeptidase (GGT) is a well known cell plasma membrane and serum circulating enzyme. In clinical chemistry, GGT is used as a marker of alcohol consumption and drug uptake. Serum GGT activity varies in hepatobiliary diseases and cancer. This enzyme is involved in glutathione (GSH) metabolism, which is generally associated with antioxidant properties. However, in recent years, fi...

Nanomaterials are widely used in cosmetics, foods and medicinal products for improved performance. In addition, various nanomaterials are under development for different biomedical applications. However, it is gradually becoming evident that many of the nanomaterials can induce substantial inflammation. For example, it is shown that metal and metal oxide nanoparticles generate oxidative stress ...

the growing demand for enhanced esthetic appearance has led to great developments in bleaching products. the exposure of hard tissues of the tooth to bleaching agents can affect the roughness of the enamel surface. the freshly bleached enamel surface exposed to various surface treatments such as fluoride and other remineralizing agents have been assessed in this study. the aim of this experimen...

Background: Pro-inflammatory cytokines are associated with systemic inflammatory responses. Objective: To investigate the levels of pro-inflammatory cytokines (IL-1b, IL-6, and TNF-a) in patients with non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH) compared to healthy individuals. Methods: This case-control study was c...

Bone Morphogenetic Protein (BMP) signaling has been implicated in diverse biological processes. Although how BMP signaling regulates behaviors of endothelial cells during angiogenesis are not fully understood, increasing evidence indicate functions of BMP signaling components are essential in developmental and pathological angiogenesis. Here we review recent advances in delineating the function...