Gas liquid chromatography was employed to detect lactic acid in the cerebrospinal fluid of patients suspected of having bacterial meningitis. The technique was found to be both rapid and reliable. Differentiation between aseptic, purulent, and partially treated bacterial meningitis was readily achieved. The effectiveness of therapy in bacterial meningitis was indicated by a rapid fall in the co...

The sand fly-transmitted Toscana virus is recognized as an etiologic agent of an aseptic meningitis with a long convalescence. This infection has been reported overall in many tourists or in a seronegative population circulating in endemic Mediterranean areas (Italy, Portugal, Egypt, and Cyprus). We report a cluster of acute Toscana virus infections in the local population during the summer of ...

We studied adenosine deaminase (ADA) activity in cerebrospinal fluid (CSF) of 16 cases of tuberculous meningitis, 4 cases of cryptococcal meningitis, 5 cases of bacterial meningitis, 12 cases of eosinophilic meningitis, 26 cases of aseptic meningitis, 6 cases of carcinomatous meningitis and 108 cases with normal CSF. The mean CSF ADA values for the different groups were: 39.44 +/- 41.46, 13.00 ...

We included 685 consecutive previously healthy well appearing infants younger than 3 months with fever without known source admitted to an Emergency Department without routinely performing lumbar punctures (LP). LP was performed in 198 infants. Of these, 36 (18.1%) showed pleocytosis. Two infants less than 15 days were diagnosed with bacterial meningitis and 47 with aseptic meningitis (6.8%). L...

OBJECTIVES Identification of causative agent with estimation of cerebrospinal fluid (CSF) glucose, protein, cells is necessary for accurate diagnosis of meningitis. Unfortunately, even these facilities are not available in many areas. Reagent strips that measure glucose and protein in blood and urine can serve this task but have been used with varying results in the past. This study was carried...

The association of E.C.H.O virus type 9 with aseptic meningitis accompanied by a rash is now well known (Tyrell, 1958; Sabin, Krumbiegel, and Wigand, 1958; Lyle, 1959). We should like to record a further outbreak of such an illness in which epistaxis was a prominent feature. Cases occurred during July and August, 1961, over a period of 32 days at a Royal Air Force station in western Germany. Th...

SUMMARY Bioactive coils were developed to improve aneurysm packing and accelerate neointimal healing. Recent reports, however, have implicated these coils in the development of aseptic meningitis, perianeurysmal edema, and hydrocephalus. This report demonstrates that the same clinical phenomena can occur with the use of bare platinum coils.

This paper describes an outbreak of aseptic meningitis associated with E.C.H.O virus type 9 among members of the Royal Air Force and their families stationed in western Germany in 1961. There was a total of 44 cases. Epistaxis occurred in eight cases and in 16 there was a rash. Virus was isolated from faeces in 11 of 24 cases examined and from cerebrospinal fluid in three out of six.

A 5-h PCR assay (Amplicor enterovirus test) was compared with viral culture for the detection of enteroviruses in cerebrospinal fluid. Of the cerebrospinal fluid specimens collected during a summer outbreak of aseptic meningitis, 34% were positive by viral culture whereas 66% were positive by the Amplicor PCR, suggesting that this technique improves the diagnosis of enteroviral meningitis.