The ability of dietary hydrated sodium calcium aluminosilicate (HSCAS), diatomite and activated charcoal (AC) in reducing the detrimental effects of aflatoxin B1 (AFB1) in broiler diets was evaluated. Adsorbents were supplemented at 2.5 g/kg to the diets containing 0, 40 or 80 μg AFB1/kg feed. One hundred and eighty Ross 308, day-old male broilers were assigned to 12 treatments for 42 days. AFB...

Abstract Background The accurate and comprehensive evaluation of liver reserve function is crucial for daily follow-up medical treatment patients with disease. However, existing techniques are too complex costly universal implementation.To develop a convenient, reliable method to evaluate based on eight biochemical indicators measured from venous blood. Methods Blood test results (albumin (Alb)...

Background: Hepatotoxicity is one of the most important side effects anticonvulsant drugs. This study compared hepatotoxicity sodium valproate, carbamazepine, phenytoin, lamotrigine, and vigabatrin in male rats. Methods: Based on results, 56 rats were randomly divided into seven groups eight treated intraperitoneally for four weeks. Groups 1 2 received 500 mg/kg carbamazepine 3, 4, 5 injected w...

Three enzymatic routes toward ?-hydroxy-?-amino acids by tandem aldol addition–transamination one-pot two-step reactions are reported. The approaches feature an enantioselective addition of pyruvate to various nonaromatic aldehydes catalyzed trans-o-hydroxybenzylidene hydratase-aldolase (HBPA) from Pseudomonas putida. This affords chiral 4-hydroxy-2-oxo acids, which were subsequently enantiosel...

BACKGROUND Piperine is isolated from Piper nigrum popularly known as black pepper. Previous studies have demonstrated the beneficial effects of piperine in various health conditions. Additionally, it is a powerful bioenhancer for many drugs. Piperine extract is believed to potentiate the effect of drugs by several folds. The present study is focused on its individual effect on liver function. ...

BACKGROUND Petroselinum crispum, a bright green biennial shrub is widely used traditionally as a food additive and herbal remedies for many ailments. This study therefore aimed to assess the toxic effects of its leaf extract using some biochemical, haematological parameters. METHODS The toxic effects were assessed by quantifying liver enzymes such as serum aspartate amino transferase (AST), a...

Abstract The present study was carried out to determine the synergistic role of vitamin E and C in reducing toxic effects cadmium chloride on some blood parameters (RBC count, Hb concentration, PCV, Total WBC Differential count), as well biochemical which include (Malondialdehyde (MDA), Aspartate aminotransferase(AST), Alanine aminotransferase (ALT), Alkaline phosphatase(ALP), Creatinin, Urea) ...

Background: This study investigated selenium nanoparticles’ protective effects (SE-NPs) against carbon tetrachloride (CCl4)-induced hepatic injury in rats. Methods: Rats were divided into four groups (n = 8). Group 1 rats received the vehicle solution only. 2 a single intraperitoneal injection of mL/kg CCl4 liquid paraffin (1:1 v/v). 3 was treated with SE-NPs (2.5 mg/kg) twice week for three we...

Abnormal liver function tests are not uncommon encounter in diabetes mellitus patients. The aim of this study was to find out the liver function test abnormalit ies in a group of d iabetic patients in Myanmar and to determine the factors associated with these biochemical changes. In this cross sectional study conducted at the diabetic clinic of Yangon General Hospital, Myanmar between March 200...