Hien Kiem Nguyen Thanh, MD, Jason Andrade, MD, Katia Dyrda, MD, MSc, PEng, Bernard Thibault, MD, FHRS, Paul Khairy, MD, Laurent Macle, MD, FHRS From the Electrophysiology Service, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Quebec, Canada, and Electrophysiology Service, Vancouver General Hospital, Department of Medicine, University of British Columbia, Va...

OBJECTIVES This study sought to assess the impact of continuous flow left ventricular assist devices (LVADs) on functional capacity and heart failure-related quality of life. BACKGROUND Newer continuous-flow LVAD are smaller and quieter than pulsatile-flow LVADs. METHODS Data from advanced heart failure patients enrolled in the HeartMate II LVAD (Thoratec Corporation, Pleasanton, California...

Left ventricular assist devices have become standard therapy for patients with end-stage heart failure. They represent potential long-term solutions for a growing public health problem. However, initial enthusiasm for this technology has been tempered by challenges posed by long-term support. This review examines these challenges and out current understanding of their etiologies.

Background/Introduction As a consequence of limited donor availability, there has been a growing interest for alternative strategies, such as left ventricular assist devices (LVAD) as either a bridge to transplantation (BTT) or as destination therapy (DT) for the treatment of the advanced heart failure. The heart transplant program in Kazakhstan is in a nascent stage and therefore patients that...

The evolution of Microelectronics has made the application of Programmable Logic Devices (PLDs) inevitable in modern digital circuit designs and when they are deployed in Safety Systems, their Reliability and Safety need to be proved beyond doubt. The design will have to meet the stringent requirements. This paper provides a review of commercially available PLDs and the design methodologies to ...

This paper was originally presented to the 2005 Annual UK-CMG Conference in Warwickshire, UK. At that time, details on z/9 109 server and z/OS V1R7 were not available. That paper was accepted for presentation by the Computer Measurement Group at the 2005 CMG International Conference. The CMG Program Committee required that the final paper be submitted no later than September 16 . By that paper ...

Cardiac transplantation represents one of the great triumphs in modern medicine and remains the cornerstone in the treatment of advanced heart failure. In this review, we contextualize pivotal developments in our understanding and management of cardiac transplant immunology, histopathology, rejection surveillance, drug development and surgery. We also discuss current limitations in their applic...

Left ventricular assist devices (LVADs) have revolutionized the care of heart failure. They now provide another therapeutic option for many patients, transplant eligible or ineligible, with symptoms refractory to medical therapy and resynchronization therapy. For appropriately selected patients, LVADs offer improvements in both quality and length of life. The enthusiasm for LVAD use in the card...

We present a case of incessant wide-complex tachycardia in a patient with left-ventricular assist device, and discuss the differential diagnosis with an in-depth analysis of the intracardiac tracings during the invasive electrophysiologic study, including interpretation of the relative timing of the fascicular signals during tachycardia and in sinus rhythm, and interpretation of pacing and entr...