Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse cutaneous reactions to drugs. We describe the case of a 19 year old patient with SJS/TEN overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. A cytomegalovirus infection was diagnosed by Real Time Polymerase Chain Reaction (RT-PCR) detection on Bronchoalveo...

The kinetics of association and dissociation for the ouabain-Na+,K+-dependent ATPase complex have been studied in intact turkey erythrocytes as a function of external Na+ concentration, K+ concentration, and temperature. At free ligand concentrations substantially exceeding the concentration of available binding sites, the association reaction exhibits pseudo-first-order kinetics with an associ...

Granulomatous response in association with breast cancer and within the cancer draining lymph nodes is an extremely rare phenomenon. Granulomatous inflammation is an immune response commonly seen against infectious agents and certain non-neoplastic conditions. The etiopathogenesis of granulomas associated with malignancies is not clear but it may be because of an immunologic reaction to tumour ...

conclusions the results of the study show no significant association between norepinephrine transporter polymorphism scl6a2 and adhd. results the percentages of adhd subtypes for combined, inattentive, and hyperactive/impulsive were 72.2%, 17.2%, and 11.9%, respectively. there was no significant association between norepinephrine transporter polymorphism and adhd (p = 0.81). moreover, no signif...

Non-necrotizing epithelioid granulomas have been described in association with many primary tumors. In such cases, they are designated as sarcoid-like reaction. Although it is more seen in carcinomas than in sarcomas, it is very rarely reported in renal carcinoma. Here, we describe a rare association of prominent peritumoral sarcoid-like reaction without intratumoral granulomas and conventional...

This study was designed to find out the impact of the variable number of tandem repeats (VNTR) of the tumor necrosis factor receptor 2 (TNFRSF1B) on pulmonary tuberculosis (PTB) risk in an Iranian population. This case-control study was done on 159 PTB patients and 158 healthy subjects. Bi-allelic TNFRSF1B VNTR was genotyped by polymerase chain reaction. Logistic regression analysis revealed no...

Cutaneous pseudolymphoma (PL) refers to a reactive T or B- cell proliferative disorder in reaction to some known or unknown stimuli. The most common site of involvement of pseudolymphoma is the face followed by the scalp. Because of its similarity with true lymphoma in both clinical and pathological aspects, differentiating between them is often difficult but fundamental due to their completely...

background : we investigated whether the c-819t snp of the ctla4 gene is associated with type 1 diabetes (t1d) for the egyptian population, a multi-ethnic group.  we determined if expression of the c-819t snp correlated with onset of t1d for egyptian children and the prevalence of this polymorphism with respect to gender. methods: the association of the c-819t snp in intron 1 of the ctla-4 gene...

body mass index (bmi) has been demonstrated to be associated with serum uric acid (sua) level in many developed countries, however, there is still a lack of large sample study in jiangsu province, one of the most economically developed regions in china, where fat-rich diet is common.through retrospective analysis in healthy subjects, we determined the association of bmi with hyperuricemia risk....

arthralgia is a common presenting symptom of many rheumatic diseases. vitamin d deficiency may lead to progression of skeletal symptoms to definite disease in susceptible subjects. this study was conducted to determine the relationship between vitamin d deficiency and unexplained arthralgia. patients with arthralgia not related to a definite clinical condition were selected prospectively among ...