Many people with asthma do not achieve disease control, despite bronchodilators and inhaled corticosteroid therapy. People with uncontrolled asthma are at higher risk of an asthma attack and death, with mortality rates estimated at 1000 deaths/year in England and Wales. The recent National Review of Asthma Deaths (NRAD) report, 'Why asthma still kills', recommended that patients at step 4 or 5 ...

Background: Asthma is a chronic inflammatory disease characterized by increased infiltration of various inflammatory cells into airway. Several previous studies showed specific immunotherapy improved clinical features of asthma due to aeroallergens. Objective: To describe the efficacy of house dust immunotherapy in childhood asthma with house dust allergy. Methods: The asthmatic patients were c...

OBJECTIVE To analyze the knowledge of asthma and its management in Spanish school teachers using the Newcastle Asthma Questionnaire (NAKQ). DESIGN Descriptive, observational prevalence study, using a self-report questionnaire on knowledge about childhood asthma and its management by teachers in pre-school, primary, and secondary schools in nine Spanish cities. Age, sex, academic training, tea...

OBJECTIVES The aim of this study was to estimate the prevalence of respiratory symptoms and physician-diagnosed asthma and assess the impact of current occupational exposure. DESIGN Cross-sectional analyses of the prevalence of self-reported respiratory health and association with current occupational exposure in a random sample of the general population in Telemark County, Norway. SETTINGS...

BACKGROUND Pediatric asthma is the No. 1 chronic disease in childhood and is responsible for significant morbidity and mortality. In Nebraska, the number of asthma-related deaths is greater than the national average, and in 1998, 2 students died of acute asthma attacks while attending school in the Omaha public schools (OPSs). In response, we designed and implemented a program to respond to thi...

Abstract Beta-adrenergic blocking agents (abbreviated as beta-blockers) have been used for treating various cardiovascular diseases. However, the potential asthma exacerbation is one of major adverse effects beta-blockers. This study aimed to compare level risk an attack in patients receiving We searched randomized controlled trials (RCTs) either placebo-controlled or active-controlled design. ...

Near-fatal asthma (NFA) is defined as the most severe form of characterized by a refractory attack with an arterial carbon dioxide tension (PaCO2) greater than 45 mmHg and altered consciousness, requiring mechanical ventilation. We reported case 40-year-old female patient, obese asthmatic irregular treatment who presented dyspnea accompanied oppressive chest pain loss generalized cyanosis short...

corticosteroids are recommended for emergency management of an asthmatic attack. this study was designed to compare the effectiveness of oral and intramuscular steroid on spirometric results in acute asthma. we performed a randomized trial involving 88 adults, aged 15-70 years, with acute exacerbation of asthma requiring treatment with steroids. all had been treated with standard bronchodilator...

Thirty-two patients with clinical diagnosis of bronchial asthma were evaluated. Serum IgE levels, measured by the Phadebas IgE test, were clearly increased in the patients with asthmatic attack compared with those without asthmatic attack. When the patients were grouped according to the clinical grading of severity of asthmatic attack, the levels showed the significant elevation in proportion t...

Nebulized budesonide (NB) might offer topical anti-inflammatory activity and be an alternative to systemic corticosteroid (SC) in the treatment of acute asthma. The aim of this study was to compare the effect of NB with SC on lung function and clinical findings of adult patients with acute asthma. Thirty patients admitted to clinic with asthma attack (F/M: 26/4; mean age: 47.1 +/- 2.1 years) we...