Activation of the large conductance, Ca2+-dependent K+ channel [KCa1.1+b-subunits, generally known as the Big K (BK) or maxi K channel] is an important negative feedback on depolarization and Ca2+-induced contraction of smooth muscle and thus arterial vasoconstriction (Figure 1). Intriguingly, altered function of BK and/or polymorphism in human BK aand b-subunit genes have been associated with ...

Immobilization stress causes marked elevation in different biogenic amines serotinin, melatonin and histamine in rat brain tissue. Oral administration of a herbomineral drug, Geriforte significantly reduced these elevated levels of biogenic amines indicating that the drug Geriforte has a significant antistress property. Several drugs have been introduced during the recent past for decreasing an...

L are used commonly in agricultural systems Legume mulches are important sources of N for cereal crop producas a source of N for subsequent crops and for maintion, particularly for organic and resource-poor producers. A field taining soil N levels. This use is particularly important study was conducted using a direct method to determine if the amount in the humid tropics where N fertilizers oft...