نتایج جستجو برای: atm

تعداد نتایج: 13493  

1997
Tien V. Do Hung T. Tran

Asynchronous Transfer Mode (ATM) is accepted as the suitable technique to realize the concept of Broadband Integrated Service Digital Networks which support diierent kinds of services such as voice, video and data in the future. However, from the economic point of view the new ATM technology has to inter-work with other existing network technologies such as TCP/IP in which the worldwide compute...

Journal: :Molecular cell 2008
Aaron A Goodarzi Angela T Noon Dorothee Deckbar Yael Ziv Yosef Shiloh Markus Löbrich Penny A Jeggo

Ataxia Telangiectasia Mutated (ATM) signaling is essential for the repair of a subset of DNA double-strand breaks (DSBs); however, its precise role is unclear. Here, we show that < or =25% of DSBs require ATM signaling for repair, and this percentage correlates with increased chromatin but not damage complexity. Importantly, we demonstrate that heterochromatic DSBs are generally repaired more s...

Journal: :The Journal of biological chemistry 2001
S Burma B P Chen M Murphy A Kurimasa D J Chen

A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2AX at serine 139 at the sites of DNA damage. Although the phosphatidylinositol 3-kinases, DNA-PK (DNA-dependent protein kinase), ATM (ataxia telangiectasia mutated), and ATR (ATM and Rad3-related), have all been implicated in H2AX phosphorylation, the specific kinase involved has...

2018
Venturina Stagni Claudia Cirotti Daniela Barilà

Ataxia-telangiectasia mutated kinase (ATM) plays a central role in the DNA damage response (DDR) and mutations in its gene lead to the development of a rare autosomic genetic disorder, ataxia telangiectasia (A-T) characterized by neurodegeneration, premature aging, defects in the immune response, and higher incidence of lymphoma development. The ability of ATM to control genome stability severa...

2007
Arjan Durresi Raj Jain

Asynchronous transfer mode (ATM) is a cell-oriented switching and multiplexing technology that uses fixed-length (53 byte; 48 bytes of data, and 5 bytes of header information) packets — called cells — to carry various types of traffic, such as data, voice, video, multimedia, and so on, through multiple classes of services. ATM is a 1 connection-oriented technology, in which a connection is esta...

2011
Kazuhiro Miyauchi

[ATM Switch] High speed ATM switch LSIs which used in B-ISDN have been developed. In 1990, 100Mbp/s BiCMOS ATM switch were reported [Kato et al., 1990]. And in 1991, a 400Mb/s 8X8 ATM switch has been developed. It realized total switch throughput of 3.2Gb/s with a 0.8mm BiCMOS technology [Tanaka et al., 1991]. A CMOS chip set for a 1.28Gb/s 16X16 output buffer ATM switch has been developed. Thi...

2003
Mansoor Alam Balachandar Swami

This paper summarizes the results of a set of simulations of error control schemes for transmission of ATM cells in Wireless and Satellite ATM networks. For Wireless ATM networks, we consider a scheme which incorporates separate FECs for ATM cell header and payload. This scheme is an effective scheme and achieves a trade-off between coding rate and bandwidth. A concatenated FEC scheme (RSCCC) i...

1994
Kai-Yeung Siu Raj Jain

Asynchronous Transfer Mode (ATM) has emerged as the most promising technology in supporting future broadband multimedia communication services. To accelerate the deployment of ATM technology, the ATM Forum, which is a consortium of service providers and equipment vendors in the communication industries, has been created to develop implementation and speci cation agreements. In this article, we ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Shaun P Scott Regina Bendix Philip Chen Raymond Clark Thilo Dork Martin F Lavin

The human genetic disorder ataxia-telangiectasia (A-T) is characterized by hypersensitivity to ionizing radiation and an elevated risk of malignancy. Epidemiological data support an increased risk for breast and other cancers in A-T heterozygotes. However, screening breast cancer cases for truncating mutations in the ATM (A-T mutated) gene has failed largely to reveal an increased incidence in ...

2016
Andrea Prodosmo Amelia Buffone Manlio Mattioni Agnese Barnabei Agnese Persichetti Aurora De Leo Marialuisa Appetecchia Arianna Nicolussi Anna Coppa Salvatore Sciacchitano Carolina Giordano Paola Pinnarò Giuseppe Sanguineti Lidia Strigari Gabriele Alessandrini Francesco Facciolo Maurizio Cosimelli Gian Luca Grazi Giacomo Corrado Enrico Vizza Giuseppe Giannini Silvia Soddu

BACKGROUND Variant ATM heterozygotes have an increased risk of developing cancer, cardiovascular diseases, and diabetes. Costs and time of sequencing and ATM variant complexity make large-scale, general population screenings not cost-effective yet. Recently, we developed a straightforward, rapid, and inexpensive test based on p53 mitotic centrosomal localization (p53-MCL) in peripheral blood mo...

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