We present the case of a 45-year-old woman with recent onset of dipnea and atrial fibrillation. She was referred to our center for treatment of an associated ventricular septal defect. Echocardiography confirmed the presence of a membranous ventricular septal defect, but also showed signs of constriction. Cardiac computed tomography displayed a severe, diffuse calcified pericarditis. We show th...

The affinity of some chromosomal anomalies for certain types of congenital heart disease is well known, e.g. atrioventricular defects in Down's syndrome and coarctation of the aorta in Turner's syndrome. Many reports on several types of congenital heart disease in close or more distant family relationships have aroused suspicion that genetic factors may be important also in other patients. Repo...

We report a woman with atrial septal defect and severe pulmonary hypertension with 25.0 Wood unit.m(2) of indexed total pulmonary vascular resistance. She underwent successful corrective repair of atrial septal defect after 2 years of treatment with sildenafil, and has been monitored for 4 years after repair. This case supports a "treat and repair" approach using advanced pulmonary vasodilator ...

BACKGROUND Pulmonary valve infective endocarditis is a rare finding for endocarditis. Infective endocarditis caused by Gemella morbillorum remains a scanty occurrence. CASE PRESENTATION This is a case reported of a 28-year-old Chinese male with endocarditis caused by pulmonary valve infection of Gemella morbillorum associated with congenital ventricular septal defect, atrial septal defect and...

While atrial septal defect (ASD) classifies as the most common cause of grown-up congenital heart (GUCH) disease, it can present with unconventional symptoms, owing to underlying pathophysiological alterations.[1]Atypical chest pain in ASD be due arrhythmias, right ventricular dysfunction, or ischemia. However, we describe an interesting echocardiographic finding, showcasing a rare potential le...

Atrial septal aneurysm (ASA) is a localised "saccular" deformity which protrudes to the right or the left atrium or on both sides. It is a rare, but well recognised cardiac abnormality. It is usually an incidental finding or may presents as atrial arrhythmias or arterial embolism. Though it is an acyanotic congenital heart disease but it may result in significant right to left shunt and cyanosi...

Co-occurrence of atrial septal defect and pulmonary valve stenosis is a rare entity for adult population. It is possible to correct both the pulmonary stenosis and the defect in the atrial septum by transcatheter methods. We present a case of right to left shant due to severe pulmonary stenosis and atrial defect which was successfully corrected by transcatheter pulmonary valvuloplasty and closu...

The heart is the first functioning organ to develop during embryogenesis. The formation of the heart is a tightly regulated and complex process, and alterations to its development can result in congenital heart defects. Mutations in sarcomeric proteins, such as alpha myosin heavy chain and cardiac alpha actin, have now been associated with congenital heart defects in humans, often with atrial s...

OBJECTIVE Congenital heart diseases are among the most frequent major congenital anomalies. One of the suspected reasons for congenital heart defects is overweight and obesity of mother during prepregnancy and pregnancy. We studied the relationship between maternal overweight and obesity and the risk of congenital anomaly. METHODS All of children with congenital heart defect (164 infants with...