CLINICAL HISTORY This is a 38-year-old G2 right-handed woman seen at 28 weeks gestation for headaches. At the age of 13, she started having migraines with aura that were frequent for several years and then became less so for many years. During her prior pregnancy 3 years ago, she had 3 migraines with aura. She had no other similar headaches until 2 months ago. She reports 9 episodes with 4 occu...

Objective To determine the prevalence, impact, and stability of different subtypes of headache in a 30 year prospective follow-up study of a general population sample. Design Prospective cohort study. Setting Canton of Zurich, Switzerland. Participants 591 people aged 19-20 from a cohort of 4547 residents of Zurich, Switzerland, interviewed seven times across 30 years of follow-up. Main outcome...

BACKGROUND The aim of this study was to investigate the thickness of the retinal nerve fiber layer (RNFL), the ganglion cell layer (GCL), and choroid thickness (CT) in patients who have migraines, with and without aura, using spectral optical coherence tomography (OCT). METHODS Forty-five patients who had migraines without aura (Group 1), 45 patients who had migraines with aura (Group 2), and...

OBJECTIVE To determine the prevalence, impact, and stability of different subtypes of headache in a 30 year prospective follow-up study of a general population sample. DESIGN Prospective cohort study. SETTING Canton of Zurich, Switzerland. PARTICIPANTS 591 people aged 19-20 from a cohort of 4547 residents of Zurich, Switzerland, interviewed seven times across 30 years of follow-up. MAIN...

OBJECTIVES To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke. DESIGN Prospective cohort study. SETTING Women's Health Study, United States. PARTICIPANTS 27,860 women aged >or=45 who were free from stroke or other major disease at baseline and had provided information on self reported migraine, aura status, and lipid values. MAIN OUTCOM...

Magnesium sulphate has been used in the acute treatment of migraines; some studies found it to be a highly effective medication in the acute control of migraine pain and associated symptoms. This randomized, double-blind, placebo-controlled study assesses the effect of magnesium sulphate on the pain and associated symptoms in patients with migraine without aura and migraine with aura. Sixty pat...

AURA is an AI-motivated system with a healthy intersection with the sciences: its short-term goal is to enable domain experts to construct declarative knowledge bases (KBs) from 50 pages of a science textbook for Physics, Chemistry, and Biology in a way that another user can pose questions similar to those in an Advanced Placement (AP) exam and get answers and explanations. In building AURA, an...

CONTEXT Migraine is considered to be an episodic condition with no long-term consequences. However, recent studies suggest that migraine attacks may be associated with pathologic changes in the brain, particularly in the cerebellum. OBJECTIVE To determine whether individuals not reporting headache compared with individuals reporting migraine symptoms, particularly aura, in midlife are at incr...

Conflicting data on cognitive defects in migraine could be explained by differences in the clinical variables of the populations studied. We investigated 21 patients with migraine with aura and 24 with migraine without aura, diagnosed according to the International Headache Society criteria. The patients were submitted to a comprehensive battery of neuropsychological tests and grouped according...

Patients with migraine with aura often experience a variety of visual and somatosensory phenomena and disturbances of higher cortical functions. Analysis of these alterations may provide important information about the involvement of different cortical regions in cortical spreading depression (CSD). We report five cases of migraineurs who experience unusually abundant clinical phenomena during ...