نتایج جستجو برای: autoimmune lymphoproliferative syndrome
تعداد نتایج: 678796 فیلتر نتایج به سال:
Journal:
:Journal of Translational Medicine
2010
Journal:
:American Journal of Hematology
2000
Journal:
:British Journal of Haematology
2009
Journal:
:Journal of Allergy and Clinical Immunology
2017
Journal:
:The Journal of Experimental Medicine
2004
Martin A. Kriegel
Tobias Lohmann
Christoph Gabler
Norbert Blank
Joachim R. Kalden
Hanns-Martin Lorenz
In autoimmune polyglandular syndromes (APS), several organ-specific autoimmune diseases are clustered. Although APS type I is caused by loss of central tolerance, the etiology of APS type II (APS-II) is currently unknown. However, in several murine models, depletion of CD4(+) CD25(+) regulatory T cells (T(regs)) causes a syndrome resembling human APS-II with multiple endocrinopathies. Therefore...
Journal:
:The Journal of Immunology
2011
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