نتایج جستجو برای: autoimmune myositis

تعداد نتایج: 69470  

2014
Nobuyoshi Mori Polly Williams Jeffrey Tarrand Zhi-Dong Jiang Herbert Dupont Javier Adachi

Rods in Cancer Patients Nobuyoshi Mori, MD; Polly Williams, MT(ASCP), CIC; Jeffrey Tarrand, MD; ZhiDong Jiang, MD, PhD; Herbert Dupont, MD, FIDSA; Javier Adachi, MD, FIDSA; Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX; Laboratory Medicine, University of Texas MD Anderson Cancer Center, Houston, TX; Center for Infectious D...

2015
Andrew L. Mammen Livia Casciola-Rosen Lisa Christopher-Stine Thomas E. Lloyd Kathryn R. Wagner

OBJECTIVE To determine the specificity of myositis-specific autoantibodies (MSAs) for autoimmune myopathy compared with inherited muscle diseases. METHODS Serum samples from 47 patients with genetically confirmed inherited muscle diseases were screened for the most common MSAs, including those recognizing TIF1γ, NXP2, Mi2, MDA5, Jo1, SRP, and HMGCR. We compared these results with the findings...

2017
Sarah L. Tansley Stefania Simou Gavin Shaddick Zoe E. Betteridge Beverley Almeida Harsha Gunawardena Wendy Thomson Michael W. Beresford Angela Midgley Francesco Muntoni Lucy R. Wedderburn Neil J. McHugh

OBJECTIVES Juvenile myositis is a rare and heterogeneous disease. Diagnosis is often difficult but early treatment is important in reducing the risk of associated morbidity and poor outcomes. Myositis specific autoantibodies have been described in both juvenile and adult patients with myositis and can be helpful in dividing patients into clinically homogenous groups. We aimed to explore the uti...

Journal: :Clinical and experimental rheumatology 2000
T Nojima M Hirakata S Sato T Fujii A Suwa T Mimori Y Ikeda

This report describes the case of a 47-year old man who developed myositis in association with hepatitis B surface antigen-positive hepatitis. Interestingly, the myositis repeatedly worsened 2 months after the exacerbation of hepatitis in this case, suggesting a close association between hepatitis B infection and myositis. The dose of prednisolone was increased twice in order to treat the exace...

Journal: :European journal of immunology 2010
Nicolas Prevot Claire Briet Hans Lassmann Isabelle Tardivel Edwige Roy Joëlle Morin Tak W Mak Anna Tafuri Christian Boitard

NOD mice spontaneously develop insulin-dependent diabetes around 10-40 wk of age. Numerous immune gene variants contribute to the autoimmune process. However, genes that direct the autoimmune response toward β cells remain ill defined. In this study, we provide evidence that the Icos and Icosl genes contribute to the diabetes process. Protection from diabetes in ICOS(-/-) and ICOSL(-/-) NOD mic...

2013
Lisa G. Rider Mona Shah Gulnara Mamyrova Adam M. Huber Madeline Murguia Rice Ira N. Targoff Frederick W. Miller

The juvenile idiopathic inflammatory myopathies (JIIM) are systemic autoimmune diseases characterized by skeletal muscle weakness, characteristic rashes, and other systemic features. In follow-up to our study defining the major clinical subgroup phenotypes of JIIM, we compared demographics, clinical features, laboratory measures, and outcomes among myositis-specific autoantibody (MSA) subgroups...

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