There is limited evidence on the efficacy of awake prone positioning (PP) in non-ventilated patients with COVID-19 who have hypoxemia. We, therefore, aim to describe our experience use early proning awake, non-intubated confirmed COVID-19. In retrospective observational study, 23 positive PCR test results for Severe Acute respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and hypoxemia that requir...

Abstract Introduction Obstructive sleep apnea (OSA) is difficult to diagnose and leads significant complications, including poor rest heart disease. Identification of OSA in patients typically requires a polysomnogram, which includes acquisition electroencephalogram (EEG) signals order assist with identification stages. Recent advancements signal processing technology, topological data analysis...

Cortical mapping has demonstrated a wide variability in the location of areas controlling speech, memory, motor and sensory function. These regions of the cortex, often referred to as eloquent cortex, can be near areas of epileptic foci or pathologic lesions, making the surgical resection of these lesions difficult. Optimal assessment of eloquent cortex function during a craniotomy often requir...

It is unclear how the complex spatiotemporal organization of ongoing cortical neuronal activity recorded in anesthetized animals relates to the awake animal. We therefore used two-photon population calcium imaging in awake and subsequently anesthetized rats to follow action potential firing in populations of neurons across brain states, and examined how single neurons contributed to population ...