Tanr?’n?n varl??? kan?tlama (isbât-? vâcib) kelâm ilminin di?er tüm meselelerin kendisine dayand??? en ba?ta gelen gayesidir. Kelâmc?lar?n özelli?i in?a ettikleri bir bilgi teorisi ekseninde bunu ortaya koymaya çal??malar?d?r. Kelâmda mevcut, ma’dum, kadîm, muhdes, cevher, araz gibi ontolojik kavramlar?n daha genelde bilinenler (malumat) kümesinin unsurlar? olmas?ndan da anla??laca?? üzere kela...

Lytic granule (LG)-mediated apoptosis is the main mechanism by which CTL kill virus-infected and tumorigenic target cells. CTL form a tight junction with the target cells, which is called the immunological synapse (IS). To avoid unwanted killing of neighboring cells, exocytosis of lytic granules (LG) is tightly controlled and restricted to the IS. In this study, we show that in activated human ...

AIMS Our aim was to evaluate the invasive haemodynamic indices of high-risk symptomatic patients presenting with 'paradoxical' low-flow, low-gradient, severe aortic stenosis (AS) (PLF-LG) and low-flow, low-gradient severe AS (LEF-LG) and to compare clinical outcomes following transcatheter aortic valve implantation (TAVI) among these challenging AS subgroups. METHODS AND RESULTS Of 534 sympto...

Backgrounds. Magnifying endoscopy with narrow-band imaging (NBI-ME) is useful for diagnosing differentiated early gastric cancer (D-EGC). D-EGC is classified as high- or low-grade based on its glandular architectural and cytological atypia. Low-grade, well-differentiated tubular adenocarcinoma (LG-tub1) mixed with high-grade tub1 (HG-tub1) and/or other histological types (M-LG-tub1) may indicat...

We investigated the possible regulatory role of glycogen in insulin-stimulated glucose transport and insulin signaling in skeletal muscle. Rats were preconditioned to obtain low (LG), normal, or high (HG) muscle glycogen content, and perfused isolated hindlimbs were exposed to 0, 100, or 10,000 microU/ml insulin. In the fast-twitch white gastrocnemius, insulin-stimulated glucose transport was s...

We present a new probabilistic sequential algorithm for stable sorting n uniformly distributed keys in an arbitrary range. The algorithm runs in linear time with very-high probability 1 ? 2 ?(n) (the best previously known probability bound has been 1 ? 2 ?(n=(lg n lg lg n))). We also describe an EREW PRAM version of the algorithm that sorts in O((n=p + lg p) lg n= lg (n=p + lg n)) time using p ...

Background and Objectives: The new CDC guideline for hand hygiene recommends either to use an antimicrobial soap or an alcohol-based hand rub supplemented with agents conferring persistent activity for surgical hand antisepsis. The most common agent which is thought to offer this latter type of effect is chlorhexidine gluconate. However, although often claimed, this effect has, to the best of o...

This paper presents a cut-elimination proof for the logic LG, which is an extension of a proof system for encoding generic judgments, the logic FOλ of Miller and Tiu, with an induction principle. The logic LG, just as FOλ, features extensions of first-order intuitionistic logic with fixed points and a “generic quantifier”, ∇, which is used to reason about the dynamics of bindings in object syst...

We studied the expression of cell surface antigens associated with myeloid and lymphoid leukemias on bone marrowderived blast cells from 339 patients with newly diagnosed de novo acute myeloid leukemia (AML) enrolled on Cancer and Leukemia Group B (CALGB) chemotherapy protocols. Surprisingly, of 211 cases studied for the expression of CD2 (T-cell marker, sheep erythrocyte binding receptor for T...

Results: The EG and LG group had 343 and 430 Rb patients respectively. The incidence of Rb in 1997 and in 2012 was 0.06 and 0.03 per 1,000 live births in Saudi Arabia respectively. The gender distribution was similar. The median age of presentation was 24 (range 11, 39) months in EG vs. 18 (8, 31) months in LG (p <0.001). Incidence of unilateral Rb was 58% [200/343] in EG vs. 56% [278/485] in L...