BACKGROUND The insulin receptor (IR) exists in two isoforms, A and B, and the isoform expression pattern is tissue-specific. The C-terminus of the insulin B chain is important for receptor binding and has been shown to contact the IR just adjacent to the region where the A and B isoforms differ. The aim of this study was to investigate the importance of the C-terminus of the B chain in IR isofo...

The decommissioning of a nuclear power plant is an immense engineering effort requiring an array of specialist tools and techniques. The decommissioning activities generate large quantities of lowactivity waste. For economic disposal, it is desirable to certify the waste as suitable for free release. Every container must be assayed to a sufficient degree of accuracy and sensitivity so that it m...

The objective of U.S. fisheries management, as mandated by National Standard 1 of the Sustainable Fisheries Act of 1996, is to maintain fish stocks at levels sufficient to produce maximum sustainable yields (MSY). Mandated levels of fishing may be less than MSY but are not to exceed these levels. MSY, of course, has been a highly elusive goal (Larkin 1977). Operationally, National Standard 1 ha...

The neoclassical justification of the economic role state rests on concepts such as model economy in equilibrium, perfect competition, market failures, social efficiency and cost-benefit analysis, monopolies, ex-ternalities, theory public goods existence free riders. All this doctrine, which is used by economists to justify interventionism, can be critici-sed from theoretical methodological ten...

<p style='text-indent:20px;'>The spectrum structure of the linearized Boltzmann operator has been a subject interest for over fifty years and inspected in space <inline-formula><tex-math id="M2">\begin{document}$ L^2\left( {\mathbb R}^d, \exp(|v|^2/4)\right) $\end{document}</tex-math></inline-formula> by B. Nicolaenko [<xref ref-type="bibr" rid="b27">27</x...

<p style='text-indent:20px;'>Ensemble Kalman Inversion (EnKI) [<xref ref-type="bibr" rid="b23">23</xref>] and Ensemble Square Root Filter (EnSRF) rid="b36">36</xref>] are popular sampling methods for obtaining a target posterior distribution. They can be seem as one step (the analysis step) in the data assimilation method rid="b17">17</xref>,<xref rid="b3"...

The use of biodiesel can reduce dependence on diesel, and the compression ignition (CI) engine's performance with is substantially low but could be improved by emulsifying nano-additives. Biodiesel production in CI engines using a homogeneous catalyst less efficient, expensive, time-consuming. In this research article, magnesium-doped calcium oxide (Mg–CaO), novel heterogeneous nanocatalyst, wa...